Description |
epidermal growth factor receptor |
heat shock protein 90 alpha family class A member 1 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Rifabutin
- Nedocromil
- 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine
- Geldanamycin
- 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
- 9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine
- 4-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic Acid
- 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
- 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-Ylamine
- 9-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine
- 4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole
- 9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine
- 9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine
- 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
- Quercetin
- 8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine
- 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
- N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE
- Tanespimycin
- SNX-5422
- N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE
- 4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
- 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE
- 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide
- 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE
- 2-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide
- 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
- (3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one
- 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE
- 3-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE
- N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE
- 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE
- 4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol
- CCT-018159
- 4-chloro-6-{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl}benzene-1,3-diol
- 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE
- 4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine
- (5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime
- 8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-
- 4-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol
- 2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol
- 2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide
- 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine
- 4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine
- 3,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
- 2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE
- Copper
- Polaprezinc
- Alvespimycin
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Diseases |
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GWAS |
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- Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
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Interacting Genes |
412 interacting genes:
ABL2
ACTA1
ADRM1
AGTR1
AHNAK
AHSA1
AIP
AKAP12
ALCAM
ALDOA
AMH
ANKS1A
ANKS1B
ANXA1
AOPEP
AP2B1
APBA3
APBB1
APBB3
APP
APPL1
AR
AREG
ARF4
ARHGEF12
ARHGEF7
ARRB2
ATIC
ATP1A1
ATP1B1
ATP5F1C
AXL
B4GALT1
BAIAP2
BCAR3
BLK
BLNK
BMX
BTC
CALM1
CALM2
CALM3
CAMK2A
CAMK2G
CAMLG
CASP1
CAV1
CAV2
CAV3
CBL
CBLB
CBLC
CCDC88A
CD44
CD59
CD82
CDC25A
CDC34
CDH1
CDH5
CDK1
CEACAM1
CEBPB
CEND1
CFL1
CLNK
CLTA
CLTCL1
CMTM8
CNOT9
CNTN2
COL9A3
CRK
CSRP1
CTNNB1
CTNND1
CTTN
CYLC2
DCBLD2
DCN
DCTN2
DEGS1
DNAJC4
DOK2
DOK4
DOK5
DOK6
DUSP19
DUSP3
DYNC1H1
EGF
ELF3
EPB41
EPHA2
EPPK1
EPS15
EPS8
ERBB2
ERBB3
ERBB4
EREG
ERRFI1
ESR1
EZR
FAH
FANCC
FAS
FBXO25
FER
FES
FGR
FKBP4
FKBP8
FN1
FRAT2
FRK
GAB1
GABARAPL2
GAPDH
GGA1
GGA3
GJB1
GNAI2
GNAS
GOT1
GPM6B
GPNMB
GRAP2
GRB10
GRB14
GRB2
GRB7
GRIN2B
GRK2
H3-4
HBEGF
HCK
HDAC6
HDAC7
HEBP1
HEMGN
HEXIM1
HGS
HOXC10
HPN
HSH2D
HSP90AA1
HSP90AB1
HSP90B1
HSPA1A
HSPA4
HSPA8
HTT
ICAM1
IKBKG
IL13RA2
IL5RA
ILKAP
INPPL1
IQGAP1
IRS1
IRS4
ITGA5
ITGB1
ITGB2
ITK
ITSN2
JAK2
JUP
KCTD9P2
KEAP1
KRT17
KRT18
KRT7
KRT8
LAT
LCK
LCP2
LINC01139
LRP1
LRRK1
LYN
MAP2K1
MAP3K12
MAP3K14
MAP3K3
MAP4K1
MAPK1
MAPK14
MAPK3
MAPK8
MAPK8IP1
MAPK8IP2
MAPK9
MAPT
MAST1
MATR3
MDH1
MEGF6
MET
MGARP
MIF
MOB4
MT-CO2
MTDH
MUC1
MUC4
NANS
NCAM1
NCK1
NCK2
NDN
NEDD4
NF2
NIBAN2
NR3C1
NRG1
NTRK2
NUMB
NUMBL
OAZ1
OLFM1
PAK1
PCNA
PDCD6IP
PDGFRA
PDGFRB
PDK3
PDP1
PFKP
PHKG1
PIK3C2A
PIK3C2B
PIK3CA
PIK3R1
PIK3R2
PIK3R3
PIM1
PIN4
PITPNA
PKIA
PLCG1
PLCG2
PLD1
PLD2
PLEC
PLSCR1
PML
POM121L12
PPARG
PPM1A
PPM1B
PPP2CB
PPP3CB
PPP5C
PRCC
PRDX1
PRKACA
PRKAR1A
PRKAR1B
PRKCA
PRKCB
PRKCD
PRKCE
PRKCZ
PRKD1
PSMA7
PSMD4
PTGDS
PTK2
PTK2B
PTK6
PTPN1
PTPN11
PTPN12
PTPN18
PTPN2
PTPN20
PTPN22
PTPN6
PTPN7
PTPRB
PTPRH
PTPRJ
PTPRR
PTPRS
PTPRT
PTPRU
RAB31
RAB3A
RAF1
RAP1GDS1
RAPGEF1
RASA1
RGS16
RGS2
RGS4
RIN1
RIN2
RIPK1
RNF115
RNF126
RNF144A
RRAD
RUSC2
S100A4
S100A7
S100A9
SCAMP1
SCAMP3
SEC13
SELENOP
SFN
SGSM2
SH2B1
SH2B2
SH2B3
SH2D1A
SH2D1B
SH2D2A
SH2D3A
SH2D3C
SH3BGRL3
SH3GL3
SHB
SHC1
SHC2
SHC3
SHC4
SHD
SHE
SLA
SLA2
SLC3A2
SLC9A3R1
SMURF2
SNCA
SNRPD2
SNX1
SNX2
SNX4
SNX6
SNX9
SOCS1
SOCS2
SOCS3
SOCS4
SOCS5
SOCS6
SOCS7
SORBS2
SOS1
SOS2
SPARCL1
SPCS2
SRC
STAG3L4
STAM2
STAP1
STAP2
STAT1
STAT2
STAT3
STAT5A
STAT5B
STIP1
STX17
STYX
SUPT6H
SYK
TAB1
TEC
TGFA
TGFB1
TJP1
TLN1
TLR2
TMCO3
TNC
TNFRSF1A
TNK2
TNS1
TNS2
TNS3
TNS4
TPI1
TPM1
TRAF2
TRMO
TRPV1
TSTD2
TUBA1A
TUBA4A
TXK
TXN
UBB
UBE2V2
UROD
VAPA
VAV1
VAV2
VAV3
WASF3
WASL
XRCC6
YES1
YWHAB
YWHAQ
YWHAZ
ZAP70
ZNF510
ZPR1
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207 interacting genes:
A1BG
A2M
AGT
AHR
AHSA1
AHSA2P
AHSG
AIP
AIPL1
AKT1
AKT2
APAF1
APOA1
APOA4
APOB
APOE
AR
ARNTL
ASGR1
BIRC5
BRMS1
C3
C4A
C4BPA
CACYBP
CALM1
CDC37
CDC37L1
CDK4
CDK5R1
CDKN2A
CERS2
CFB
CFTR
CHEK1
CHORDC1
CHUK
CKS1B
CKS2
COL12A1
CP
CRNKL1
CSNK2A1
CSNK2A2
DAP3
DCD
DNAJC7
EGFR
EGLN1
EIF2AK1
EIF2AK2
EIF2AK3
EIF2S1
EPAS1
EPRS1
ERBB2
ERN1
ESR1
ESRRB
FAM162A
FANCC
FASN
FGA
FKBP1A
FKBP4
FKBP5
FKBP6
FLCN
FLG2
FN1
FNIP1
FYN
GABARAPL1
GC
GNA12
GSK3A
GSK3B
GSN
GUCY1B1
GZMA
HDAC6
HIF1A
HIF3A
HP
HPR
HPX
HRNR
HSF1
HSPA8
HSPG2
HTT
IGHA2
IGHD
IKBKB
IKBKE
IKBKG
IP6K2
IRAK1
IRF3
ITGB1BP2
ITIH1
JUN
JUP
KDR
KEAP1
LCK
LGALS3BP
LINC01554
LOXL2
LRP1
LSM1
MAP3K14
MAP3K3
MAPK1
MAPT
MED28
MIS12
MMP2
MS4A2
MTRNR2L1
MUC1
MYC
MYOD1
NDRG1
NOS1
NOS3
NPAS2
NR2C2
NR3C1
NR3C2
NSL1
OGT
PABPN1
PAK1
PDPK1
PHLDA2
PIM1
PKM
PLG
PMF1
PPARA
PPARD
PPID
PPIL2
PPP5C
PRKACA
PRKCA
PRKCD
PRKDC
PTGDS
PTGES3
PTPRF
RAD51
RAF1
RHOBTB2
RIPK1
RPAP3
RPS3
RPS3A
RUNX1T1
SERPINA1
SERPINA3
SERPINB5
SERPINC1
SERPING1
SGTA
SHKBP1
SIM1
SKP1
SLC2A4
SLC34A1
SMYD2
SMYD3
SNCA
SRC
ST13
STARD13
STAT3
STIP1
STUB1
SUGT1
SUMO2
SVIL
TBK1
TCIRG1
TERT
TF
THBS1
TJP1
TLN1
TNFRSF1A
TOMM34
TOMM40
TOMM70
TP53
TTK
TTR
UBASH3A
UBE2N
UCHL1
UNC45A
USP13
USP19
USP50
WASL
YWHAE
YWHAZ
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Entrez ID |
1956 |
3320 |
HPRD ID |
00579 |
00777 |
Ensembl ID |
ENSG00000146648
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ENSG00000080824
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Uniprot IDs |
B7Z2I3
E7BSV0
E9PFD7
F2YGG7
P00533
Q504U8
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K9JA46
P07900
Q86SX1
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PDB IDs |
1DNQ
1DNR
1IVO
1M14
1M17
1MOX
1NQL
1XKK
1YY9
1Z9I
2EB2
2EB3
2EXP
2EXQ
2GS2
2GS6
2GS7
2ITN
2ITO
2ITP
2ITQ
2ITT
2ITU
2ITV
2ITW
2ITX
2ITY
2ITZ
2J5E
2J5F
2J6M
2JIT
2JIU
2JIV
2KS1
2M0B
2M20
2N5S
2RF9
2RFD
2RFE
2RGP
3B2U
3B2V
3BEL
3BUO
3C09
3G5V
3G5Y
3GOP
3GT8
3IKA
3LZB
3NJP
3OB2
3OP0
3P0Y
3PFV
3POZ
3QWQ
3UG1
3UG2
3VJN
3VJO
3VRP
3VRR
3W2O
3W2P
3W2Q
3W2R
3W2S
3W32
3W33
4G5J
4G5P
4HJO
4I1Z
4I20
4I21
4I22
4I23
4I24
4JQ7
4JQ8
4JR3
4JRV
4KRL
4KRM
4KRO
4KRP
4LI5
4LL0
4LQM
4LRM
4R3P
4R3R
4R5S
4RIW
4RIX
4RIY
4RJ4
4RJ5
4RJ6
4RJ7
4RJ8
4TKS
4UIP
4UV7
4WD5
4WKQ
4WRG
4ZAU
4ZJV
4ZSE
5C8K
5C8M
5C8N
5CAL
5CAN
5CAO
5CAP
5CAQ
5CAS
5CAU
5CAV
5CNN
5CNO
5CZH
5CZI
5D41
5EDP
5EDQ
5EDR
5EM5
5EM6
5EM7
5EM8
5FED
5FEE
5FEQ
5GMP
5GNK
5GTY
5GTZ
5HCX
5HCY
5HCZ
5HG5
5HG7
5HG8
5HG9
5HIB
5HIC
5J9Y
5J9Z
5JEB
5LV6
5SX4
5SX5
5U8L
5UG8
5UG9
5UGA
5UGB
5UGC
5UWD
5WB7
5WB8
5X26
5X27
5X28
5X2A
5X2C
5X2F
5X2K
5XDK
5XDL
5XGM
5XGN
5XWD
5Y25
5Y9T
5YU9
5ZTO
5ZWJ
6ARU
6B3S
6D8E
6DUK
6JRJ
6JRK
6JRX
6JWL
6JX0
6JX4
6JXT
6JZ0
6LUB
6LUD
6P1D
6P1L
6P8Q
6S89
6S8A
6S9B
6S9C
6S9D
6TFU
6TFV
6TFW
6TFY
6TFZ
6TG0
6TG1
6V5N
6V5P
6V66
6V6K
6V6O
6VH4
6VHN
6VHP
6Z4B
6Z4D
7A2A
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1BYQ
1OSF
1UY6
1UY7
1UY8
1UY9
1UYC
1UYD
1UYE
1UYF
1UYG
1UYH
1UYI
1UYK
1UYL
1YC1
1YC3
1YC4
1YER
1YES
1YET
2BSM
2BT0
2BUG
2BYH
2BYI
2BZ5
2C2L
2CCS
2CCT
2CCU
2FWY
2FWZ
2H55
2JJC
2K5B
2QF6
2QFO
2QG0
2QG2
2UWD
2VCI
2VCJ
2WI1
2WI2
2WI3
2WI4
2WI5
2WI6
2WI7
2XAB
2XDK
2XDL
2XDS
2XDU
2XDX
2XHR
2XHT
2XHX
2XJG
2XJJ
2XJX
2XK2
2YE2
2YE3
2YE4
2YE5
2YE6
2YE7
2YE8
2YE9
2YEA
2YEB
2YEC
2YED
2YEE
2YEF
2YEG
2YEH
2YEI
2YEJ
2YI0
2YI5
2YI6
2YI7
2YJW
2YJX
2YK2
2YK9
2YKB
2YKC
2YKE
2YKI
2YKJ
3B24
3B25
3B26
3B27
3B28
3BM9
3BMY
3D0B
3EKO
3EKR
3FT5
3FT8
3HEK
3HHU
3HYY
3HYZ
3HZ1
3HZ5
3INW
3INX
3K97
3K98
3K99
3MNR
3O0I
3OW6
3OWB
3OWD
3Q6M
3Q6N
3QDD
3QTF
3R4M
3R4N
3R4O
3R4P
3R91
3R92
3RKZ
3RLP
3RLQ
3RLR
3T0H
3T0Z
3T10
3T1K
3T2S
3TUH
3VHA
3VHC
3VHD
3WHA
3WQ9
4AIF
4AWO
4AWP
4AWQ
4B7P
4BQG
4BQJ
4CGQ
4CGU
4CGV
4CGW
4CWF
4CWN
4CWO
4CWP
4CWQ
4CWR
4CWS
4CWT
4EEH
4EFT
4EFU
4EGH
4EGI
4EGK
4FCP
4FCQ
4FCR
4HY6
4JQL
4L8Z
4L90
4L91
4L93
4L94
4LWE
4LWF
4LWG
4LWH
4LWI
4NH7
4NH8
4O04
4O05
4O07
4O09
4O0B
4R3M
4U93
4W7T
4XIP
4XIQ
4XIR
4XIT
4YKQ
4YKR
4YKT
4YKU
4YKW
4YKX
4YKY
4YKZ
5CF0
5FNC
5FND
5FNF
5GGZ
5J20
5J27
5J2V
5J2X
5J64
5J6L
5J6M
5J6N
5J80
5J82
5J86
5J8M
5J8U
5J9X
5LNY
5LNZ
5LO0
5LO1
5LO5
5LO6
5LQ9
5LR1
5LR7
5LRL
5LRZ
5LS1
5M4E
5M4H
5NYH
5NYI
5OCI
5OD7
5ODX
5T21
5VYY
5XQD
5XQE
5XR5
5XR9
5XRB
5XRD
5XRE
5ZR3
6B99
6B9A
6CEO
6CYG
6CYH
6EI5
6EL5
6ELN
6ELO
6ELP
6EY8
6EY9
6EYA
6EYB
6F1N
6FCJ
6FDP
6GP4
6GP8
6GPF
6GPH
6GPO
6GPP
6GPR
6GPT
6GPW
6GPY
6GQ6
6GQR
6GQS
6GQU
6GR1
6GR3
6GR4
6GR5
6HHR
6KSQ
6LR9
6LSZ
6LT8
6LTI
6LTK
6N8X
6OLX
6TN4
6TN5
6U98
6U99
6U9A
6U9B
7LSZ
7LT0
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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