DLST and FLII

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLST	FLII
Description		dihydrolipoamide S-succinyltransferase	FLII actin remodeling protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Membrane Centriolar Satellite Oxoglutarate Dehydrogenase Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Brush Border Focal Adhesion Actin Cytoskeleton Centriolar Satellite
	Molecular Function	Dihydrolipoyllysine-residue Succinyltransferase Activity Protein Binding Acyltransferase Activity	Actin Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle 2-oxoglutarate Metabolic Process Succinyl-CoA Metabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Histone Succinylation	Actin Polymerization Or Depolymerization Myofibril Assembly Actin Filament Severing Barbed-end Actin Filament Capping
Pathways		Glyoxylate metabolism and glycine degradation Lysine catabolism Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Eosinophil counts ( 32888494) Mood instability ( 29187730) Non-small cell lung cancer ( 23144319)
Interacting Genes		19 interacting genes: ACYP1 ARIH2 CCDC86 DLG5 ESRRB FLII NAP1L1 NDRG1 OGDH OGT PAK4 PFN2 RUSC2 SCFD1 SIAH2 TUBB4B UMPS ZBTB16 ZHX1	14 interacting genes: ACTB ACTL6A CARM1 DLST ESR1 GRIP1 LRRFIP1 LRRFIP2 MAPK7 MYD88 NCOA2 OPTN PRMT1 TRAIP
Entrez ID		1743	2314
HPRD ID		00520	02647
Ensembl ID		ENSG00000119689	ENSG00000177731
Uniprot IDs		A0A024R6C9 B7Z6J1 P36957	Q13045
PDB IDs		6H05
Enriched GO Terms of Interacting Partners?
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