NUDT10 and PDLIM7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NUDT10	PDLIM7
Description		nudix hydrolase 10	PDZ and LIM domain 7
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Stress Fiber Ruffle Nucleoplasm Cytosol Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Filamentous Actin
	Molecular Function	Endopolyphosphatase Activity Protein Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity Metal Ion Binding M7G(5')pppN Diphosphatase Activity Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding
	Biological Process	Diphosphoinositol Polyphosphate Metabolic Process Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process	Ossification Receptor-mediated Endocytosis Heart Development Actin Cytoskeleton Organization Cell Differentiation Positive Regulation Of Osteoblast Differentiation Muscle Structure Development
Pathways		Synthesis of pyrophosphates in the cytosol	RET signaling
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Prostate cancer ( 18264097 18264098)	Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: HSF2BP MTUS2 PDLIM7 RASSF1 REL SNAPC5 TCF4 TRIM8	63 interacting genes: ABI2 AP5B1 BAG3 BSG CATSPER1 CCDC185 CDK12 DDX6 DGCR6 DNER ENKD1 FAM214B FAM71C FAM90A1 FNDC11 FRS3 GEM GFAP GPATCH2L HEY2 HNRNPD HNRNPF HSF2BP HSPB7 IL16 IQGAP1 KANK2 MDM2 NUDT10 OTUD6A PAK5 PARVG PCBP1 PHF1 PIN1 PLEKHN1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RASGEF1B RET RPP25 SCNM1 SH2B2 SH3BP2 SLAIN1 SMURF1 SPP1 TCF19 TNPO2 TP53 TPM2 TRAF2 TRAF3 TSG101 TSGA10IP UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		170685	9260
HPRD ID		17651	10436
Ensembl ID		ENSG00000122824	ENSG00000196923
Uniprot IDs		Q8NFP7	Q9NR12
PDB IDs		3MCF	2Q3G
Enriched GO Terms of Interacting Partners?
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