SLC30A8 and REEP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC30A8	REEP6
Description		solute carrier family 30 member 8	receptor accessory protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Integral Component Of Membrane Secretory Granule Transport Vesicle Membrane Secretory Granule Membrane Cytoplasmic Vesicle	Photoreceptor Inner Segment Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Clathrin-coated Vesicle Membrane
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Zinc Ion Transport Cellular Zinc Ion Homeostasis Response To Glucose Response To Zinc Ion Insulin Secretion Positive Regulation Of Insulin Secretion Sequestering Of Zinc Ion Response To Interferon-gamma Glucose Homeostasis Regulation Of Vesicle-mediated Transport Regulation Of Sequestering Of Zinc Ion Response To Interleukin-1 Zinc Ion Transmembrane Transport	Endoplasmic Reticulum Organization Regulation Of Intracellular Transport Detection Of Light Stimulus Involved In Visual Perception
Pathways		Insulin processing Zinc efflux and compartmentalization by the SLC30 family	Olfactory Signaling Pathway
Drugs
Diseases
GWAS		Asthma ( 21814517) Blood sugar levels ( 29403010) Body mass index ( 28892062) Fasting blood glucose ( 33842983 25631608 20081858 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Fasting blood glucose adjusted for BMI ( 25625282) Fasting blood proinsulin levels ( 23263489) Fasting glucose ( 33402679 34059833) Fasting plasma glucose ( 25187374 28270201) Glycated hemoglobin levels ( 24647736 34059833 19096518 28898252) Glycemic traits (pleiotropy) ( 31021400) Hemoglobin A1c levels ( 29403010) Insulin-related traits (multivariate analysis) ( 32002517) Intraocular pressure ( 24002674) Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Lung cancer ( 27393504) Medication use (drugs used in diabetes) ( 31015401) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Proinsulin levels ( 21873549) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Type 2 diabetes ( 27189021 22885922 24509480 17293876 30054458 22693455 26961502 29358691 30297969 19734900 29632382 26818947 31217584 23945395 31118516 32499647 20581827 19401414 17463246 30718926 17463248 17463249 28869590 17460697 19056611) Type 2 diabetes (adjusted for BMI) ( 29632382) Vestibular neuritis ( 30079052)
Interacting Genes		70 interacting genes: ANK1 AQP6 ARL8B ATP13A1 BCL2L13 BSND CCL4 CD99L2 CGRRF1 CMTM7 CPLX4 CREB3L1 DERL1 ELOVL4 ERVFRD-1 FAM209A FAM210B FAXDC2 FCER1G GPR37L1 GPR42 GRM2 HMOX2 HSD17B11 JSRP1 LEUTX LMNA MUC1 NKG7 ORMDL1 OTULINL PCNA PGRMC2 PKMYT1 PLN PSCA PTPN9 REEP4 REEP6 RELL2 RMDN3 RTN3 RUSF1 SCN3B SELENOK SFT2D1 SFT2D2 SLC18A1 SLC30A3 SLC39A2 SYS1 SYT2 THAP4 THSD7B TMEM11 TMEM139 TMEM14B TMEM208 TMEM237 TMEM31 TMEM50A TMEM52B TMEM80 TMEM9 TSPAN2 VAMP1 VAMP2 YIPF4 YIPF6 ZFYVE27	48 interacting genes: ADAT3 ARL6IP1 ATP5PF CD79A CDC37 CERT1 COQ8A CYB561 EBAG9 FHIP1B GJA8 GORASP2 GPR152 HMBOX1 HSD17B13 IZUMO4 KRTAP3-1 LEPROTL1 LITAF LMNA LNX1 MIEF2 NDRG4 NTAQ1 PICK1 PTPN9 RETREG3 RPS20 SCAMP4 SDCBP SLC30A8 SNX1 SNX11 SNX15 SNX8 SPG21 STING1 SYT16 TLCD4 TMED8 TMEM143 TMEM259 TMPPE TNS2 TXN2 WIPI2 ZFYVE21 ZNF554
Entrez ID		169026	92840
HPRD ID		15370	16629
Ensembl ID		ENSG00000164756	ENSG00000115255
Uniprot IDs		Q8IWU4	A0A1L5BXV2 Q96HR9
PDB IDs		6XPD 6XPE 6XPF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?