DFFA and DFFB

Number of citations of the paper that reports this interaction (PubMedID 9422506)
506

Data Source:
HPRD (in vivo, in vitro)

		DFFA	DFFB
Description		DNA fragmentation factor subunit alpha	DNA fragmentation factor subunit beta
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane Protein-containing Complex	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding Protein Folding Chaperone Deoxyribonuclease Inhibitor Activity	DNA Binding Endodeoxyribonuclease Activity Deoxyribonuclease Activity Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Disordered Domain Specific Binding
	Biological Process	Apoptotic DNA Fragmentation Negative Regulation Of Deoxyribonuclease Activity Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Chaperone-mediated Protein Folding Thymocyte Apoptotic Process Negative Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Apoptotic DNA Fragmentation	DNA Catabolic Process Apoptotic DNA Fragmentation Apoptotic Chromosome Condensation
Pathways		Apoptosis induced DNA fragmentation	Apoptosis induced DNA fragmentation
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Male-pattern baldness ( 29146897 28196072)	Blood trace element (Cu levels) ( 23720494) Metabolite levels ( 23823483)
Interacting Genes		11 interacting genes: CASP3 CASP7 CIDEB DFFB EWSR1 GZMB GZMM NECAB2 STRN4 YWHAG YWHAZ	4 interacting genes: APP CIDEB DFFA TOP2A
Entrez ID		1676	1677
HPRD ID		03531	03532
Ensembl ID		ENSG00000160049	ENSG00000169598
Uniprot IDs		A0A024R4H5 O00273	B4DZS0 O76075 Q96P72 Q96P73 Q96P74
PDB IDs		1IBX 1IYR 1KOY	1IBX
Enriched GO Terms of Interacting Partners?
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