DAPK1 and BAIAP2

Number of citations of the paper that reports this interaction (PubMedID 29513927)
16

Data Source:
BioGRID (pull down)

		DAPK1	BAIAP2
Description		death associated protein kinase 1	BAR/IMD domain containing adaptor protein 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Actin Cytoskeleton	Ruffle Nucleoplasm Cytoplasm Rough Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Plasma Membrane Adherens Junction Actin Cytoskeleton Lamellipodium Secretory Granule Filopodium Neuronal Cell Body Dendritic Shaft Neuron Projection Terminus Excitatory Synapse Neuron Projection Branch Point Dendritic Spine Cytoplasm Extracellular Exosome Synaptic Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Postsynaptic Density, Intracellular Component Presynaptic Cytosol Postsynaptic Cytosol
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding GTP Binding Syntaxin-1 Binding Identical Protein Binding Protein Serine Kinase Activity	Transcription Coregulator Binding Protein Binding Protein C-terminus Binding Cytoskeletal Anchor Activity PDZ Domain Binding Identical Protein Binding Proline-rich Region Binding Scaffold Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Defense Response To Tumor Cell Protein Phosphorylation Apoptotic Process Regulation Of Autophagy Positive Regulation Of Autophagy Negative Regulation Of Translation Intracellular Signal Transduction Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Autophosphorylation Cellular Response To Interferon-gamma Cellular Response To Hydroperoxide Apoptotic Signaling Pathway Regulation Of NMDA Receptor Activity	Plasma Membrane Organization Axonogenesis Brain Development Insulin Receptor Signaling Pathway Regulation Of Cell Shape Response To Bacterium Dendrite Development Positive Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Protein Localization To Synapse Regulation Of Synaptic Plasticity Actin Filament Bundle Assembly Actin Crosslink Formation Positive Regulation Of Dendritic Spine Morphogenesis Cellular Response To Epidermal Growth Factor Stimulus Cell-cell Adhesion Modification Of Synaptic Structure, Modulating Synaptic Transmission Cellular Response To L-glutamate Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Positive Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		Caspase activation via Dependence Receptors in the absence of ligand	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs CDC42 GTPase cycle RAC1 GTPase cycle RAC3 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs		5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine Phosphoaminophosphonic Acid-Adenylate Ester 6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE Fostamatinib
Diseases
GWAS		Blood pressure ( 24954895) Cognitive function ( 24684796) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Height ( 31562340) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Night sleep phenotypes ( 27126917) Ovarian cancer ( 30557369) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to gemcitabine in pancreatic cancer ( 22293537)	Adult body size ( 32376654) Adverse response to drug ( 30420678) Beef consumption ( 32066663) Body size at age 10 ( 32376654) Breast cancer ( 29871690) Daytime nap ( 33568662) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Feeling tense ( 29500382) General factor of neuroticism ( 30867560) Memory performance ( 24392092) Neurociticism ( 29500382) Neuroticism ( 29255261) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		107 interacting genes: ABL1 ABLIM1 AHDC1 APEX2 ARRDC1 ARRDC1-AS1 ATF6 BAG2 BAIAP2 C11orf65 CALM1 CAPRIN1 CBLB CCDC149 CDC42EP3 CDC42SE1 CMTM4 CNTROB DENND1C DTWD1 DUS1L DUX3 EPHA1 FADD FAM107A FAM126B FBXL14 FBXW11 FIBP GASK1B GTF2F1 IKBKG JHY LIMA1 LIMS1 LINC02875 LMF2 LNX1 LOXL2 MAPK1 MAPK3 MCM10 MDM2 MIB1 MRGBP MTHFD2 MYL12B NCBP3 NECAB1 NECAP1 NR3C1 ORMDL2 PAK6 PAPSS2 PCP4 PHKG2 PIM1 PIM2 POLR2M PPP1R14A PPP2R1A PPP2R2D PPP2R5A PRKAG2 PRR16 PWP1 RAPGEF3 RASGRP2 RCHY1 RFC5 RHBDD1 RPAP3 RPL41 SARNP SCEL SCRN3 SCYL1 SGK2 SH2D2A SLAIN2 SNRPA SNURF SNX9 SPATS2 SPRR2G SRSF10 STARD3 STUB1 STX1A TAS2R60 TBC1D22B TNFRSF1A TPD52L1 TRADD TRAPPC2 TTC27 TUBB4B UNC5A UNC5B UNC5C VGLL4 VN1R1 WWTR1 YWHAB ZAP70 ZMAT4 ZMYM5	41 interacting genes: ADGRB1 APP ATN1 BAIAP2L1 C19orf25 CDC42 COG6 DAPK1 DIAPH1 EGFR ENAH EPS8 ERG28 ESPN GRB10 HOXD8 KANK1 KDM1A LIN7A LIN7B LIN7C MARK2 NCKIPSD NEDD4 OGT PAK1 PBX2 PRR13 RAC1 RTN4 SF3A2 SF3B4 SHANK1 SHANK2 SHANK3 SRPK2 TBX5 TP53BP2 WASF1 WASF2 YWHAG
Entrez ID		1612	10458
HPRD ID		02902	05686
Ensembl ID		ENSG00000196730	ENSG00000175866
Uniprot IDs		B4DHI4 P53355 Q59H88	I3L4C2 Q9UQB8
PDB IDs		1IG1 1JKK 1JKL 1JKS 1JKT 1P4F 1WVW 1WVX 1WVY 1YR5 2W4J 2W4K 2X0G 2XUU 2XZS 2Y0A 2Y4P 2Y4V 2YAK 3DFC 3DGK 3EH9 3EHA 3F5G 3F5U 3GU4 3GU5 3GU6 3GU7 3GU8 3GUB 3ZXT 4B4L 4PF4 4TL0 4TXC 4UV0 4YO4 4YPD 5AUT 5AUU 5AUV 5AUW 5AUX 5AUY 5AUZ 5AV0 5AV1 5AV2 5AV3 5AV4 6AAR 6FHA 6FHB 6GY5 6IN4 6QMO 6QN4 7CCU 7CCV 7CCW	1WDZ 1Y2O 2YKT 3RNJ 4JS0 6BCR 6BCY 6BD1 6BD2 6BQT 6ZEG 6ZEI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?