AP2A2 and KCNQ1DN

		AP2A2	KCNQ1DN
Description		adaptor related protein complex 2 subunit alpha 2	KCNQ1 downstream neighbor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane AP-2 Adaptor Complex Endocytic Vesicle Membrane Secretory Granule Membrane Clathrin-coated Endocytic Vesicle Membrane Cytoplasmic Vesicle Endolysosome Membrane Clathrin-coated Endocytic Vesicle Ficolin-1-rich Granule Membrane	Cellular_component
	Molecular Function	Molecular_function Protein Binding Lipid Binding Protein Kinase Binding Clathrin Adaptor Activity Disordered Domain Specific Binding Cargo Adaptor Activity	Molecular_function
	Biological Process	Intracellular Protein Transport Receptor-mediated Endocytosis Clathrin-dependent Endocytosis	Biological_process
Pathways		Nef Mediated CD4 Down-regulation Retrograde neurotrophin signalling Retrograde neurotrophin signalling Nef Mediated CD8 Down-regulation MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Recycling pathway of L1 Recycling pathway of L1 WNT5A-dependent internalization of FZD4 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Neutrophil degranulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis VLDLR internalisation and degradation LDL clearance Potential therapeutics for SARS
Drugs
Diseases
GWAS		Adult asthma ( 27611488) Alzheimer's disease ( 30636644) Alzheimer's disease (late onset) ( 24162737) Asthma ( 31959851) Chronic bronchitis and chronic obstructive pulmonary disease ( 25241909) Nicotine withdrawal ( 29532581) Nicotine withdrawal symptom count ( 29532581)	Malaria ( 31844061) Plateletcrit ( 27863252)
Interacting Genes		22 interacting genes: AAGAB AMPH AP1S1 AP2B1 APP BIN1 DNAJC6 DNM1 EPN1 EPS15 HTT ILK KCNQ1DN LRPPRC NLGN3 NUMB SHC1 SLC2A8 SMAD1 SNAP91 UBC ZPR1	1 interacting genes: AP2A2
Entrez ID		161	55539
HPRD ID		06256	17174
Ensembl ID		ENSG00000183020	ENSG00000237941
Uniprot IDs		O94973
PDB IDs
Enriched GO Terms of Interacting Partners?
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