TSTD2 and TOX3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TSTD2	TOX3
Description		thiosulfate sulfurtransferase like domain containing 2	TOX high mobility group box family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nucleus Nucleoplasm Cytosol
	Molecular Function	Molecular_function Protein Binding	Chromatin Binding Transcription Coactivator Activity Protein Binding Chromatin DNA Binding Protein Homodimerization Activity Phosphoprotein Binding
	Biological Process	Biological_process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) ( 32678081) Brain morphology (MOSTest) ( 32665545) Brain volume in infants (grey matter) ( 28763065) BRCA1 mutation in breast cancer ( 33597508) BRCA1/2-negative high-risk breast cancer ( 30323354) Breast cancer ( 21263130 20872241 24143190 25327703 29059683 23535729 23535733 27117709 20585626 31757997 20453838 25956309 19330030) Breast cancer (early onset) ( 24493630) Breast cancer (estrogen-receptor negative) ( 27117709) Breast cancer (male) ( 23001122) Breast cancer in BRCA2 mutation carriers ( 23544012) Chronotype ( 30696823) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Gut microbiota (bacterial taxa) ( 27723756) Hematocrit ( 32888494) Hemoglobin ( 32888494) Major depressive disorder ( 27479909) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Parkinson's disease ( 28892059) Polycystic ovary syndrome ( 22885925 30566500) Response to tofacitinib treatment (herpes zoster) ( 33455090) Response to tofacitinib treatment (herpes zoster)(time to event) ( 33455090) Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster) ( 33455090) Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster)(time to event) ( 33455090) Restless legs syndrome ( 29029846 21779176)
Interacting Genes		33 interacting genes: AGR2 APC AURKA BLZF1 BUB1 CCND1 DCC EGFR FLCN IKZF1 IKZF3 INCA1 ISY1-RAB43 L3MBTL3 LHX4 MCC MEOX2 MLH3 MUTYH ODC1 PICK1 PTPRJ REL SMAD4 SSX2IP TCF4 TOX3 VPS52 ZBTB14 ZFPL1 ZNF438 ZNF774 ZRANB1	12 interacting genes: DUSP21 FHL2 GCM2 IST1 KRTAP9-3 KRTAP9-8 NUP62CL PIN1 POM121 SEZ6L2 TLE5 TSTD2
Entrez ID		158427	27324
HPRD ID		16679	19073
Ensembl ID		ENSG00000136925	ENSG00000103460
Uniprot IDs		Q5T7W7	O15405
PDB IDs
Enriched GO Terms of Interacting Partners?
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