TTC39B and VAPB

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		TTC39B	VAPB
Description		tetratricopeptide repeat domain 39B	VAMP associated protein B and C
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Enzyme Binding FFAT Motif Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Beta-tubulin Binding
	Biological Process	Lipid Metabolic Process Regulation Of Cholesterol Efflux Negative Regulation Of Cholesterol Storage Cholesterol Homeostasis Regulation Of Cholesterol Metabolic Process	Cellular Calcium Ion Homeostasis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Modulation By Virus Of Host Process Endoplasmic Reticulum Unfolded Protein Response IRE1-mediated Unfolded Protein Response Positive Regulation Of Viral Genome Replication Endoplasmic Reticulum-plasma Membrane Tethering COPII-coated Vesicle Budding Endoplasmic Reticulum Membrane Organization
Pathways			Sphingolipid de novo biosynthesis RHOA GTPase cycle RHOC GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Bipolar disorder ( 22925353 34099189) Bipolar disorder x sex interaction ( 34099189) Cholesterol, total ( 24097068 20686565) Coenzyme Q10 levels ( 27149984) Coronary artery disease ( 29212778) Gallstone disease ( 30504769) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol ( 24097068 20864672 19060906 30275531 25961943 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) High density lipoprotein cholesterol levels ( 33339817) Hip circumference ( 28552196) Macular telangiectasia type 2 ( 33654266) Metabolite levels (lipoprotein measures) ( 27005778) Total cholesterol levels ( 28334899) Triglyceride levels ( 32203549) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
Interacting Genes		2 interacting genes: MEOX2 VAPB	42 interacting genes: AIG1 AQP2 AQP6 CD79A CYB561 CYBRD1 EBAG9 EBP ELOVL4 EMD FAM174A GLP1R GPR25 HSD17B13 JAGN1 KCNB1 MAILR MTNR1A OSBPL2 PTGES REEP4 RETREG3 RMDN2 RNASEK RNF111 SCN3B SLC22A1 SLC35C2 STX1A STX2 STX4 STX5 TMEM101 TMX2 TTC39B USP20 VAMP1 VAMP2 VHL VKORC1 ZBTB22 ZDHHC15
Entrez ID		158219	9217
HPRD ID		10801	09300
Ensembl ID		ENSG00000155158	ENSG00000124164
Uniprot IDs		Q5VTQ0	O95292 Q53XM7
PDB IDs			2MDK 3IKK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?