AGR3 and CGRRF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AGR3	CGRRF1
Description		anterior gradient 3, protein disulphide isomerase family member	cell growth regulator with ring finger domain 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Intracellular Membrane-bounded Organelle	Nucleoplasm Endoplasmic Reticulum Intracellular Membrane-bounded Organelle
	Molecular Function	Dystroglycan Binding Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Biological_process Negative Regulation Of Cell Death	Cell Cycle Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth
Pathways
Drugs
Diseases
GWAS		Coffee consumption ( 31959922 29367735) Cutaneous malignant melanoma ( 32341527 26237428) Cutaneous squamous cell carcinoma ( 32041948) Diffusing capacity of carbon monoxide ( 30694715) Lung cancer in ever smokers ( 28604730) Melanoma ( 28212542) Refractive error ( 32231278) Residual cognition ( 28441426) Rosacea symptom severity ( 29771307) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432)	Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)
Interacting Genes		36 interacting genes: AKT1 AP1B1 APC ASB10 BCAR3 BZW2 CASP8 CATSPER1 CD46 CGRRF1 CNNM3 DAG1 DESI1 EDA2R ERLIN1 ESR2 FXYD3 KRTAP11-1 LIME1 LSM1 LYPD3 MMGT1 NRM NTAQ1 NUP62 PDZK1IP1 PRAF2 PTPN1 SGTA SGTB SPINT1 TGFB1 TIMMDC1 TMEM14B UBQLN1 UBQLN2	32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1
Entrez ID		155465	10668
HPRD ID		16545	09366
Ensembl ID		ENSG00000173467	ENSG00000100532
Uniprot IDs		Q8TD06	Q99675
PDB IDs		3PH9	2EA5
Enriched GO Terms of Interacting Partners?
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