SH3RF2 and EFS

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SH3RF2	EFS
Description		SH3 domain containing ring finger 2	embryonal Fyn-associated substrate
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm Plasma Membrane Focal Adhesion
	Molecular Function	Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Phosphatase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding SH3 Domain Binding Protein Domain Specific Binding
	Biological Process	Positive Regulation Of Cell Migration Negative Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade Protein Autoubiquitination	Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Intracellular Signal Transduction Actin Filament Reorganization
Pathways
Drugs
Diseases
GWAS		Bacteremia ( 27236921) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Response to (pegylated) interferon in HBeAG-positive hepatitis B ( 30715261)
Interacting Genes		23 interacting genes: AKAP8L AMOTL2 APP ATXN7L2 BAG4 BANP CBY2 CCDC102B CYSRT1 EFS FASLG GOLGA2 HOMEZ LMNA LZTS2 MTUS2 NEK6 PAK4 PPP1CA PPP1CC RBPMS UBE2N VPS37C	36 interacting genes: ABI2 AGXT APP BCAR1 BDKRB2 BLK CCDC187 CRK FYN GLMN GPANK1 LHX8 LYST MYOZ3 NCK1 NCK2 NF1 NLGN3 NPAS2 NUP155 OSTF1 PIN1 PTK2 PTK2B PTPN12 SH2D3C SH3RF2 SORBS2 SORBS3 SRC TRAPPC6A TSSK1B UBASH3B UBC YES1 ZNF417
Entrez ID		153769	10278
HPRD ID		10229	09932
Ensembl ID		ENSG00000156463	ENSG00000100842
Uniprot IDs		Q08AM8 Q8TEC5	O43281
PDB IDs
Enriched GO Terms of Interacting Partners?
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