ZMAT2 and TSEN15

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZMAT2	TSEN15
Description		zinc finger matrin-type 2	tRNA splicing endonuclease subunit 15
Image
GO Annotations	Cellular Component	Nucleus U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome	Nucleoplasm Nucleolus
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Nucleic Acid Binding Nuclease Activity Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways			tRNA processing in the nucleus
Drugs
Diseases
GWAS		Major depressive disorder ( 27479909) Refractive error ( 32231278) Schizophrenia ( 28991256 29483656) Serum immune biomarker levels ( 32066700) Systolic blood pressure ( 30224653)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Chronotype ( 30696823) Height ( 20881960) Hip circumference adjusted for BMI ( 34021172 25673412) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Type 2 diabetes ( 32499647) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in inactive individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 34021172 25673412)
Interacting Genes		40 interacting genes: AK8 AMH BICD2 CALCOCO1 CBY2 CCDC57 CDR2 CEP76 ERBB2 FSD2 FXR1 FXR2 GOLGA2 GOLGA6L9 GRIPAP1 HAP1 HMBOX1 IKZF1 KANK2 KRT40 LZTS2 MEOX2 MTUS2 NAB2 NUTF2 PHC2 PICK1 PRPH SPAG5 SSX2IP TFEC TFIP11 TNIP1 TRAF2 TRIM36 TRIM37 TSEN15 VPS52 ZBTB14 ZBTB8A	34 interacting genes: AIF1L ARID5A ASB12 CCDC33 DDIT4L DNAAF6 ENKD1 ERBB2 EXOSC4 GORASP2 HSF2BP IKZF3 INCA1 LMO2 LMO4 LRIF1 MEI4 MIPOL1 NBPF3 PBX4 PHOSPHO2 PLB1 POLR2G POU6F2 REL TASOR2 TEPSIN TLE5 TSEN34 TSSK2 USP54 ZMAT2 ZNF554 ZNF620
Entrez ID		153527	116461
HPRD ID		08094	12292
Ensembl ID		ENSG00000146007	ENSG00000198860
Uniprot IDs		Q96NC0	A0A2U3TZM3 B1ALV0 E9PPN1 Q8WW01
PDB IDs		5O9Z 6AHD 7AAV 7ABF 7ABG 7ABI	2GW6
Enriched GO Terms of Interacting Partners?
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