RASGEF1B and PLEKHF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RASGEF1B	PLEKHF2
Description		RasGEF domain family member 1B	pleckstrin homology and FYVE domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Early Endosome Late Endosome Midbody	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity	Protein Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Small GTPase Mediated Signal Transduction Regulation Of Catalytic Activity	Protein Transport
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28552196) Cocaine dependence ( 31212010) Coronary artery disease ( 32469254 33020668) Depression in smokers ( 30219690) Diffusing capacity of carbon monoxide ( 30694715) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Height ( 25429064 31562340 18391951) Hip circumference adjusted for BMI ( 34021172) Major depressive disorder ( 23377640) Myocardial infarction ( 33532862) Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465) Plasma parathyroid hormone levels ( 30134803) Pursuit maintenance gain ( 29064472) Refractive error ( 32231278) Response to antidepressants in depression ( 29998114) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Waist circumference ( 28552196) Waist circumference adjusted for body mass index ( 34021172) White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621)	Radiation response ( 20923822)
Interacting Genes		4 interacting genes: BAZ2B PDLIM7 PLEKHF2 TSGA10IP	176 interacting genes: ABCG4 ACY3 ADAP1 AIDA AIMP2 ANO9 APP APPL1 ARID4B ARL14EP ASPH BARHL2 BCAS2 BCAS3 BEND7 BLOC1S6 BOD1 BRD7 BSCL2 C11orf45 C1orf35 C3 CAVIN2 CBX8 CCDC146 CCDC172 CCDC25 CCDC85B CDC20B CEP44 CERK CGGBP1 CHCHD2 CHIC2 COX5B CRYBA1 DAZAP2 DMRT3 DNAAF11 DOCK2 DOCK3 DPPA4 DRAP1 DTX2 DUSP4 DUT EIF3C EML2 ESRP1 EXOC7 FAH FBXO28 FBXW5 FGF13 FHL3 FLNA FOXA1 FRMD8 GAGE12G GAGE2E GEM GFER GLUL GNMT GPBP1 GPBP1L1 GRAMD4 GTPBP2 HEBP2 HEY1 HSPB7 INO80 KCNAB3 KRTAP10-10 KRTAP5-4 L3MBTL3 LDOC1 MAGI2 MAP2K1 MAX MBIP MBP MEAF6 MFAP1 MIDN MPP4 MRI1 NDUFA5 NFIA NKG7 NONO NPM2 NSD2 NUDT2 NUTM1 P2RX7 PACSIN1 PAK1IP1 PDK4 PDP1 PEX2 PIK3R3 PPCDC PPP1R18 PRDM14 PRKAG1 PRKAR1A PRPSAP1 PTPN3 PWWP2A RAB28 RAB39A RABAC1 RADX RARA RASGEF1B RGS10 RGS8 RPAP2 RPE RPRM RPS21 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SAMD11 SCYL1 SEC14L4 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SNRNP35 SOST SPATA24 SPEF1 SPON2 STAMBPL1 SYT16 TBCEL TBX3 TCEANC TCN2 THAP10 THG1L TNFAIP8 TNFAIP8L1 TP53BP2 TRAF6 TRAM1L1 TRAPPC3 TRIAP1 TRIM22 TSC22D3 TTC9C TXNL4B UBE2Z UGP2 USF1 XCR1 XRN2 YIF1A YY1 ZBTB6 ZDHHC24 ZFYVE26 ZNF165 ZNF250 ZNF263 ZNF398 ZNF439 ZNF581
Entrez ID		153020	79666
HPRD ID		17955	15147
Ensembl ID		ENSG00000138670	ENSG00000175895
Uniprot IDs		Q0VAM2	Q9H8W4
PDB IDs
Enriched GO Terms of Interacting Partners?
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