CCDC50 and MAP1LC3B

Number of citations of the paper that reports this interaction (PubMedID 32612200)
8

Data Source:
BioGRID (affinity chromatography technology, pull down, x-ray crystallography)

		CCDC50	MAP1LC3B
Description		coiled-coil domain containing 50	microtubule associated protein 1 light chain 3 beta
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol	Autophagosome Membrane Mitochondrion Autophagosome Cytosol Microtubule Axoneme Endomembrane System Organelle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Ceramide Binding
	Biological Process	Sensory Perception Of Sound	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Autophagosome Maturation
Pathways			Macroautophagy PINK1-PRKN Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 23562540) Lung cancer in never smokers ( 28604730)	General factor of neuroticism ( 30867560) Major depressive disorder ( 22472876) Metabolite levels ( 23823483) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: ARRDC3 DDX58 HNRNPA1 IFIH1 MAP1LC3B MAVS NPHP3 RIPK1 RNF8 RPS3A SH3GL1 STING1 TNFAIP3 UBC	73 interacting genes: AAMP ADD1 ADNP AMBRA1 ANK2 ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BAG6 BIRC6 BNIP3 BRD3 CASP8 CCDC50 CCSER2 CLTA CUL3 DBI DBN1 DNMT3B EED EPS8 EVA1A FLCN FUNDC1 GABARAPL2 GORASP2 IRGQ KBTBD7 KLHL5 KXD1 LUC7L2 MESD MKRN1 MRFAP1 MYBL2 NEDD4 NEK9 OPTN PRKCZ RAD1 RAP1GAP RETREG2 RIPOR1 RPLP1 SEM1 SMARCB1 SNU13 SNX18 SPAG9 SQSTM1 STK3 STK4 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B TBK1 THAP7 TMOD3 TNIP1 TRIM21 TRIM32 UPF2 USP10 VHL
Entrez ID		152137	81631
HPRD ID		06463	14358
Ensembl ID		ENSG00000152492	ENSG00000140941
Uniprot IDs		Q8IVM0	Q658J6 Q9GZQ8
PDB IDs		6LAN	1V49 2LUE 2N9X 2ZJD 3VTU 3VTV 3VTW 3WAO 3X0W 4WAA 5D94 5DCN 5GMV 5MS2 5MS5 5MS6 5V4K 5W9A 5XAC 5XAD 5XAE 6J04 6LAN
Enriched GO Terms of Interacting Partners?
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