Description |
cathepsin B |
plasminogen activator, urokinase |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Amiloride
- 2-{2-hydroxy-[1,1'-biphenyl]-3-yl}-1H-1,3-benzodiazole-5-carboximidamide
- 2-(2-Hydroxy-5-Methoxy-Phenyl)-1h-Benzoimidazole-5-Carboxamidine
- 6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine
- 2-(2-hydroxy-phenyl)-3H-benzoimidazole-5-carboxamidine
- 6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine
- 6-[N-(1-Isopropyl-3,4-Dihydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine
- CRA_10655
- 6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine
- 6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine
- 7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide
- 6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide
- Benzamidine
- 4-Iodobenzo[B]Thiophene-2-Carboxamidine
- CRA_8696
- Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine
- 2-Amino-1H-benzimidazol-5-ol
- N-(1-adamantyl)-N'-(4-guanidinobenzyl)urea
- 6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine
- Thieno[2,3-B]Pyridine-2-Carboxamidine
- 8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide
- [2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine
- Fibrinolysin
- 6-fluoro-2-(2-hydroxy-3-isobutoxy-phenyl)-1H-benzoimidazole-5-carboxamidine
- 6-FLUORO-2-[2-HYDROXY-3-(2-METHYL-CYCLOHEXYLOXY)-PHENYL]-1H-INDOLE-5-CARBOXAMIDINE
- N-(4-CARBAMIMIDOYL-3-CHORO-PHENYL)-2-HYDROXY-3-IODO-5-METHYL-BENZAMIDE
- 6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE
- 1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine
- (2R)-1-(2,6-dimethylphenoxy)propan-2-amine
- 4-(2-aminoethoxy)-N-(2,5-diethoxyphenyl)-3,5-dimethylbenzamide
- 4-(2-aminoethoxy)-N-(3-chloro-2-ethoxy-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide
- 4-(2-AMINOETHOXY)-3,5-DICHLORO-N-[3-(1-METHYLETHOXY)PHENYL]BENZAMIDE
- 4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide
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Diseases |
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GWAS |
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- Blood protein levels ( 29875488)
- Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
- Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
- Crohn's disease ( 28067908)
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Interacting Genes |
37 interacting genes:
A2M
ACAN
ADAMTSL4
ANXA2
ANXA7
APOE
APP
BAG6
BGLAP
CDKN1A
CST3
CST7
CSTA
CSTB
CTSD
ERCC6
FAM118B
HNRNPD
HSPB2
IGF1
INS
MARCKS
MTDH
PARP1
PLAU
REN
RGS2
S100A10
SERPINB13
SLPI
SPHK1
SPINT2
SPRY2
SRPX2
STK11
UBQLN4
XRN1
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26 interacting genes:
ADAM28
ALAS1
BTK
CEBPG
CTSB
CTSL
ELAVL1
F2
HGF
IGF2R
KAT8
LRP2
MYC
NID1
PDGFC
PLAT
PLAUR
PLG
SCAMP5
SERPINA5
SERPINB2
SERPINB6
SERPINE1
SERPINF2
SFTPD
ST14
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Entrez ID |
1508 |
5328 |
HPRD ID |
00287 |
01883 |
Ensembl ID |
ENSG00000164733
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ENSG00000122861
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Uniprot IDs |
A0A024R374
B4DMY4
P07858
Q5HYG5
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A0A024QZM9
B4DNJ4
P00749
Q59GZ8
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PDB IDs |
1CSB
1GMY
1HUC
1PBH
2IPP
2PBH
3AI8
3CBJ
3CBK
3K9M
3PBH
5MBL
5MBM
6AY2
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1C5W
1C5X
1C5Y
1C5Z
1EJN
1F5K
1F5L
1F92
1FV9
1GI7
1GI8
1GI9
1GJ7
1GJ8
1GJ9
1GJA
1GJB
1GJC
1GJD
1KDU
1LMW
1O3P
1O5A
1O5B
1O5C
1OWD
1OWE
1OWH
1OWI
1OWJ
1OWK
1SC8
1SQA
1SQO
1SQT
1U6Q
1URK
1VJ9
1VJA
1W0Z
1W10
1W11
1W12
1W13
1W14
2FD6
2I9A
2I9B
2NWN
2O8T
2O8U
2O8W
2R2W
2VIN
2VIO
2VIP
2VIQ
2VIV
2VIW
2VNT
3BT1
3BT2
3IG6
3KGP
3KHV
3KID
3M61
3MHW
3MWI
3OX7
3OY5
3OY6
3PB1
3QN7
3U73
4DVA
4DW2
4FU7
4FU8
4FU9
4FUB
4FUC
4FUD
4FUE
4FUF
4FUG
4FUH
4FUI
4FUJ
4GLY
4H42
4JK5
4JK6
4K24
4MNV
4MNW
4MNX
4MNY
4OS1
4OS2
4OS4
4OS5
4OS6
4OS7
4X0W
4X1N
4X1P
4X1Q
4X1R
4X1S
4XSK
4ZHL
4ZHM
4ZKN
4ZKO
4ZKR
4ZKS
5HGG
5WXF
5WXO
5WXP
5WXQ
5WXR
5WXS
5WXT
5XG4
5YC6
5YC7
5Z1C
5ZA7
5ZA8
5ZA9
5ZAE
5ZAF
5ZAG
5ZAH
5ZAJ
5ZC5
6AG2
6AG3
6AG7
6AG9
6JYP
6JYQ
6L04
6L05
6NMB
6XVD
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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