SMYD1 and H3-5

Number of citations of the paper that reports this interaction (PubMedID 23455924)
46

Data Source:
BioGRID (two hybrid)

		SMYD1	H3-5
Description		SET and MYND domain containing 1	H3.5 histone
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleosome Euchromatin Barr Body Nucleus
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding	Protein Binding Nucleosomal DNA Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Remodeling Heart Development Positive Regulation Of Myotube Differentiation Histone Lysine Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated	Osteoblast Differentiation Nucleus Organization Spermatid Development Single Fertilization Embryo Implantation Cell Population Proliferation Male Gonad Development Positive Regulation Of Cell Growth Pericentric Heterochromatin Assembly Subtelomeric Heterochromatin Assembly Multicellular Organism Growth Muscle Cell Differentiation Oogenesis Regulation Of Centromere Complex Assembly Negative Regulation Of Chromosome Condensation
Pathways
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Retinal detachment or retinal break ( 31816047)
Interacting Genes		44 interacting genes: ARID5A BACH2 BHLHE40 C11orf1 C11orf16 C11orf53 CCDC113 CCDC33 DISC1 DVL1 FAM166A FAM204A FAM83A FAM86C1P H3-5 HDAC2 HDAC3 HDHD3 HMG20A HOMEZ KIF16B KRT35 LENG8 MDFI MEOX2 MYH7B NACA NEFL OGDHL PATZ1 POU6F2 PRR22 RBM4B RSPH6A RUSC1 SNX11 SPAG8 TBRG1 TTC33 USP54 UTP14A WDR77 ZBTB3 ZBTB44	15 interacting genes: DAXX DNAJC9 FBLIM1 KAT6A KDM1A KDM4B NASP NSD3 PRMT5 PRMT6 PRMT7 SETMAR SMYD1 SMYD3 SUV39H1
Entrez ID		150572	440093
HPRD ID		06025	18443
Ensembl ID		ENSG00000115593	ENSG00000188375
Uniprot IDs		E9PHG3 Q5HYE8 Q8NB12	Q6NXT2
PDB IDs			2PUY 3KV4 4Z5T 5BWN 5BWO 5F6K 5I3L 6OI3
Enriched GO Terms of Interacting Partners?
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