AANAT and EIF4E3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AANAT	EIF4E3
Description		aralkylamine N-acetyltransferase	eukaryotic translation initiation factor 4E family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Aralkylamine N-acetyltransferase Activity Arylamine N-acetyltransferase Activity Protein Binding 14-3-3 Protein Binding	RNA 7-methylguanosine Cap Binding Translation Initiation Factor Activity
	Biological Process	N-terminal Protein Amino Acid Acetylation Circadian Rhythm Response To Light Stimulus Photoperiodism Response To Zinc Ion Melatonin Biosynthetic Process Response To Insulin Response To Cytokine Response To Prostaglandin E Indolalkylamine Biosynthetic Process Response To Copper Ion Response To Corticosterone Response To Calcium Ion Cellular Response To CAMP	Translational Initiation Regulation Of Translation
Pathways		Serotonin and melatonin biosynthesis	ISG15 antiviral mechanism
Drugs		CoA-S-trimethylene-acetyl-tryptamine CoA-s-acetyl tryptamine CoA-S-acetyl 5-bromotryptamine Cannabidiol Medical Cannabis Nabiximols
Diseases
GWAS		High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494)	Apolipoprotein A1 levels ( 32203549) Chronotype ( 30696823) Cutaneous squamous cell carcinoma ( 32041948) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol levels ( 32203549) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Nose size ( 27182965) Type 2 diabetes ( 31049640)
Interacting Genes		9 interacting genes: BHLHE40 BIRC5 EIF4E3 F2 GRB10 KRTAP8-1 MDFI PRKACA YWHAZ	1 interacting genes: AANAT
Entrez ID		15	317649
HPRD ID		02974	10687
Ensembl ID		ENSG00000129673	ENSG00000163412
Uniprot IDs		F1T0I5 Q16613	Q8N5X7
PDB IDs
Enriched GO Terms of Interacting Partners?
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