UBE2U and KAT6A

Number of citations of the paper that reports this interaction (PubMedID 19690564)
64

Data Source:
BioGRID (two hybrid)

		UBE2U	KAT6A
Description		ubiquitin conjugating enzyme E2 U	lysine acetyltransferase 6A
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GO Annotations	Cellular Component	HULC Complex	Nucleosome Nucleus Nucleoplasm Nucleolus Cytosol PML Body Nuclear Speck MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Acetyltransferase Activity Histone Binding
	Biological Process	Protein Polyubiquitination DNA Repair Histone Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	DNA Packaging Nucleosome Assembly Protein Acetylation Histone Acetylation Myeloid Cell Differentiation Histone H3 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Senescence Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Severe bacterial meningitis ( 31092817)	Sleep duration ( 30531941)
Interacting Genes		68 interacting genes: ANAPC11 BARD1 BFAR CADPS2 CBL CGRRF1 DTX1 DZIP3 GOLGA2 KAT6A MDM2 MIB1 MIB2 MID2 MKRN3 MUL1 PCGF1 PCGF2 PCGF6 PJA1 PML RBCK1 RNF10 RNF11 RNF113A RNF113B RNF114 RNF125 RNF139 RNF14 RNF144B RNF150 RNF166 RNF17 RNF170 RNF181 RNF2 RNF25 RNF26 RNF41 RNF5 RNFT1 SYVN1 TRAIP TRIM15 TRIM2 TRIM23 TRIM24 TRIM27 TRIM28 TRIM3 TRIM32 TRIM34 TRIM35 TRIM37 TRIM38 TRIM46 TRIM47 TRIM5 TRIM54 TRIM63 TRIM65 TRIM68 TRIM74 UBA1 VPS11 VPS41 ZSWIM2	19 interacting genes: AKT1 ATN1 ATXN1 CREBBP H3-4 H3-5 H3C1 H3C14 H4-16 H4C1 H4C9 HEMGN MAFK PML RERE RUNX1 SPI1 TP53 UBE2U
Entrez ID		148581	7994
HPRD ID		14599	03244
Ensembl ID		ENSG00000177414	ENSG00000083168
Uniprot IDs		A0A140VJY9 Q5VVX9	A5PKX7 A5PLL3 Q92794
PDB IDs		1YRV	1M36 2LN0 2OZU 2RC4 3V43 4LJN 4LK9 4LKA 4LLB 5B75 5B76 5B77 5B78 6LSB
Enriched GO Terms of Interacting Partners?
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