MGAT5B and CREB5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		MGAT5B	CREB5
Description		alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	cAMP responsive element binding protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Chromatin Nucleus Extracellular Exosome
	Molecular Function	Protein Binding Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Manganese Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein N-linked Glycosylation Protein O-linked Glycosylation Via Serine	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Cannabis use (initiation) ( 22823124) Colorectal or endometrial cancer ( 26621817) Early cardiac repolarization ( 22683750) Nicotine dependence symptom count ( 25555482) Pulmonary emphysema ( 24383474) Refractive error ( 32231278) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)	Adolescent idiopathic scoliosis ( 31417091) Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Airflow obstruction ( 22837378) Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals ( 22959728) Anxiety in major depressive disorder ( 24047446) Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Atrial fibrillation ( 30061737 29892015) Attention deficit hyperactivity disorder ( 18839057) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 29059683) Cataracts ( 34127677) Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216) Crohn's disease ( 23128233) Diabetic retinopathy ( 21441570) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Eosinophil percentage of granulocytes ( 27863252) Ferritin levels ( 33491795) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Hand grip strength ( 29691431) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 29403010 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Pre-treatment viral load in HIV-1 infection ( 31219150) Pulse pressure ( 27841878 30578418) Serum thyroid-stimulating hormone levels ( 25436638) Smoking behaviour (cigarettes smoked per day) ( 31217584) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) TPE interval (resting) ( 32386560) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) White blood cell count ( 29403010 32888494 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		110 interacting genes: ABHD11 ADAMTSL4 ADRA2C ANAPC11 ANTKMT ATG9A ATP23 BMF C10orf55 C11orf1 C17orf50 C22orf39 CAMK2B CD46 CREB5 CSN3 CTAG1A CTAG1B CXCL5 CYSRT1 DMRT3 EIF4E2 EIF4ENIF1 FAM166B FAM83A FNDC11 FOXH1 GATA1 GLYCTK GNE HIGD2B HOXA1 HOXC8 HR HSD3B7 IGLL5 IQCE IVD KCTD17 KLHL38 KPRP KRT86 KRTAP1-1 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP22-1 KRTAP26-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-2 LASP1 LONRF1 MAGED1 MCCD1 MDFI MKRN3 MSX2 NHLRC4 OIP5 OTX1 PITX1 PLA2G10 PLSCR1 PTGER3 PTH1R PTPRZ1 R3HDM2 RBP3 RBPMS RHOXF2 RSKR RTN4R SLC16A5 SLC25A48 SMARCC1 SMUG1 SNRPC SPAG8 SSC4D STK16 SYNGAP1 TBX6 TEKT5 TENT5B TMEM42 TNS2 TRIM35 TRIM42 TRIP13 TSPAN4 TXNDC5 TYRO3 UBAP2 UNKL VAC14 ZIC1 ZNF20 ZNF414 ZNF581	132 interacting genes: ADAMTSL4 AJUBA AKAP8L ALPP ANAPC11 ATF2 BATF3 CDPF1 CERCAM CIB4 CNFN COL8A1 CYP21A2 CYSRT1 EFEMP2 FBLN1 FHL3 FOS FOSB FOSL1 FOSL2 FRS3 FST HOXA1 HSD3B7 ID3 IGFBP6 INTS11 JDP2 JUN KIFC3 KPRP KRT15 KRT31 KRT40 KRT83 KRT85 KRT86 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP19-2 KRTAP19-3 KRTAP19-5 KRTAP19-6 KRTAP2-3 KRTAP2-4 KRTAP22-1 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1C LCE2A LCE2C LCE4A LCE5A LGALS13 LITAF LMX1B MDFI MGAT5B MLLT6 MMADHC MTUS2 NADSYN1 NBPF19 NOTCH2NLA PCSK5 PLA2G10 PRDM14 PRR22 RBCK1 RBP3 RBPMS RCHY1 RGS17 RGS20 RIMBP3 RNF144B RNF208 SIVA1 SNAPC5 SPATA12 SPOP SPOPL SPRED1 SPRY1 SPRY2 SPRY3 SPRY4 SSC4D TP53BP1 TRAF2 TRIM23 TRIM27 TRIM42 TRIP6 TSGA10 TSPAN4 TSR2 UFSP1 UNKL WWOX ZMAT5 ZNF330
Entrez ID		146664	9586
HPRD ID		14392	09896
Ensembl ID		ENSG00000167889	ENSG00000146592
Uniprot IDs		Q3V5L5	Q02930
PDB IDs
Enriched GO Terms of Interacting Partners?
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