IL34 and LCE1F

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IL34	LCE1F
Description		interleukin 34	late cornified envelope 1F
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Macrophage Colony-stimulating Factor Receptor Binding Protein Binding Growth Factor Activity	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Inflammatory Response Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Macrophage Chemotaxis Positive Regulation Of MAP Kinase Activity Innate Immune Response Positive Regulation Of Macrophage Differentiation Positive Regulation Of Monocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Protein Tyrosine Kinase Activity Interleukin-34-mediated Signaling Pathway Microglial Cell Proliferation Positive Regulation Of Macrophage Proliferation	Keratinization
Pathways		Other interleukin signaling	Formation of the cornified envelope
Drugs
Diseases
GWAS		Alzheimer's disease ( 34099642) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Cerebrospinal P-tau181p levels ( 28247064) Diffuse cutaneous systemic sclerosis ( 29293537) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Intraocular pressure ( 29785010 30054594) Malaria ( 31844061)	Asthma ( 31619474)
Interacting Genes		3 interacting genes: ATXN1 LCE1F PTPRZ1	74 interacting genes: ADAMTSL4 ALPP CATSPER1 CHIC2 CHRD CRCT1 CYP21A2 CYSRT1 FBLN1 HOXA1 IL34 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE2B LCE2C LCE2D LCE3B LCE5A MACO1 MDFI NBPF19 NOTCH2NLA NTAQ1 OIT3 OTX1 PCSK5 POU4F2 PSMB1 RAD54L2 RGS20 RNF4 SLC39A7 SMCP SPRY1 SPRY2 SPRY3 TRIM42 UBE2I VWC2 WFDC3
Entrez ID		146433	353137
HPRD ID		14582	13970
Ensembl ID		ENSG00000157368	ENSG00000240386
Uniprot IDs		A0A024QZ87 Q6ZMJ4	Q5T754
PDB IDs		4DKC 4DKD 4DKE 4DKF
Enriched GO Terms of Interacting Partners?
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