FAM81A and STX1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM81A	STX1B
Description		family with sequence similarity 81 member A	syntaxin 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Microtubule Organizing Center Spindle Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Integral Component Of Membrane Axon SNARE Complex Neuromuscular Junction Presynaptic Active Zone Membrane
	Molecular Function	Protein Binding	SNARE Binding Signaling Receptor Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding Protein Domain Specific Binding
	Biological Process		Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Negative Regulation Of Neuron Projection Development Synaptic Vesicle Docking Regulation Of Exocytosis Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Activity Spontaneous Neurotransmitter Secretion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Negative Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Positive Regulation Of Excitatory Postsynaptic Potential
Pathways			Toxicity of botulinum toxin type C (botC) LGI-ADAM interactions
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Visceral adipose tissue adjusted for BMI ( 22589738)	Adult body size ( 32376654) Body mass index ( 31453325) Body mass index variance ( 31453325) Dementia with Lewy bodies ( 29263008) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Juvenile myoclonic epilepsy ( 30531953) Low density lipoprotein cholesterol levels ( 32154731) Parkinson's disease ( 25064009 32201043) Psoriasis ( 25574825) Response to metformin (IC50) ( 28173075) Waist circumference ( 31453325) Waist circumference variance ( 31453325) Walking pace ( 33128006)
Interacting Genes		7 interacting genes: NAP1L2 PCM1 RCOR3 STX1B TFIP11 TXLNA ZNF655	31 interacting genes: ABHD16A ACBD5 AQP6 BET1 EBP ERGIC3 FAM161B FAM209A FAM81A FBXO28 FGA GJA8 GPR152 KCNN4 MMGT1 NAPB NPTX1 SNAP23 SNAP29 SNAP47 STX2 STX4 STXBP1 TMEM167B TMEM219 TXLNA UBE2I UNC13B VAMP1 VAMP2 VAMP5
Entrez ID		145773	112755
HPRD ID		14508	18126
Ensembl ID		ENSG00000157470	ENSG00000099365
Uniprot IDs		Q8TBF8	P61266
PDB IDs
Enriched GO Terms of Interacting Partners?
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