CSF3R and WSB1

Number of citations of the paper that reports this interaction (PubMedID 17001306)
5

Data Source:
BioGRID (affinity chromatography technology, protein complementation assay)

		CSF3R	WSB1
Description		colony stimulating factor 3 receptor	WD repeat and SOCS box containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Endocytic Vesicle Membrane Receptor Complex	Cytosol
	Molecular Function	Cytokine Receptor Activity Protein Binding Cytokine Binding Signaling Receptor Activity Granulocyte Colony-stimulating Factor Binding	Protein Binding
	Biological Process	Defense Response Cell Adhesion Signal Transduction Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Regulation Of Myeloid Cell Differentiation Amelogenesis	Biological_process Protein Ubiquitination Intracellular Signal Transduction
Pathways		Other interleukin signaling Transcriptional regulation of granulopoiesis Signaling by CSF3 (G-CSF) Signaling by CSF3 (G-CSF) Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Pegfilgrastim Filgrastim FavId Lenograstim Lipegfilgrastim
Diseases
GWAS		Basophil count ( 32888494) Cerebrospinal fluid p-tau levels ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321) Eosinophil percentage of white cells ( 32888494) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Iron status biomarkers (total iron binding capacity) ( 28334935) Lymphocyte percentage of white cells ( 32888494 27863252) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 29403010 32888494 27863252)	Birth weight ( 31043758) Chronic myeloid leukemia ( 21540461) Dental caries ( 23064961)
Interacting Genes		20 interacting genes: CISH CSF3 ELANE FTH1 GRB2 HCK HPCA INPP5D JAK1 JAK2 LCK LYN PLA2G1B PTPN11 SHC1 SOCS3 STAT3 SYK WSB1 WSB2	8 interacting genes: CSF3R DIO2 GSK3B HIPK2 LRRK2 UBE2D2 UBE2D3 VHL
Entrez ID		1441	26118
HPRD ID		00737	15680
Ensembl ID		ENSG00000119535	ENSG00000109046
Uniprot IDs		Q99062	A0A024QZ36 A0A024QZ51 Q8NC76 Q9Y6I7
PDB IDs		1AZ7 2D9Q
Enriched GO Terms of Interacting Partners?
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