CSE1L and PPP5C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CSE1L	PPP5C
Description		chromosome segregation 1 like	protein phosphatase 5 catalytic subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytosol Plasma Membrane Protein-containing Complex Perikaryon Intracellular Membrane-bounded Organelle Chaperone Complex Proximal Dendrite
	Molecular Function	Nuclear Export Signal Receptor Activity Protein Binding Small GTPase Binding	G-protein Alpha-subunit Binding RNA Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding ATP Binding Microtubule Binding Lipid Binding Phosphatase Activity Identical Protein Binding ADP Binding Protein-containing Complex Binding Metal Ion Binding Tau Protein Binding Hsp90 Protein Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Protein Import Into Nucleus Protein Export From Nucleus	MAPK Cascade Mitotic Cell Cycle Negative Regulation Of Protein Phosphorylation Double-strand Break Repair Transcription, DNA-templated Protein Dephosphorylation Response To Lead Ion Histone Dephosphorylation Peptidyl-threonine Dephosphorylation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Morphine Peptidyl-serine Dephosphorylation Cellular Response To Hydrogen Peroxide Cellular Response To Cadmium Ion Negative Regulation Of Neuron Death Response To Arachidonic Acid Positive Regulation Of Glucocorticoid Receptor Signaling Pathway
Pathways			Negative regulation of MAPK pathway Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks ESR-mediated signaling
Drugs			ATP
Diseases
GWAS		Anger ( 24489884) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Non-response to citalopram or escitalopram and depression ( 27622933) Response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease ( 31299468) Subjective well-being ( 27089181)	Basophil percentage of white cells ( 27863252) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Hemoglobin ( 32888494) Lymphocyte counts ( 32888494) Neuroticism ( 29255261) Response to antidepressants in depression ( 29998114) Triglyceride levels ( 32203549)
Interacting Genes		20 interacting genes: BIRC2 CDC42 CDH1 DUX4 HNRNPL KPNA1 KPNA2 KPNA4 KPNA6 KPNB1 MAPK6 MTNR1B PPP5C RAN RPL22 STAT1 SUMO2 TMEM62 YWHAG YWHAQ	27 interacting genes: APP CDC16 CDC27 CDC37 CDK20 CHORDC1 CPNE1 CPNE2 CPNE4 CRY2 CSE1L CSNK1D DISC1 EGFR ESR2 GNA12 GNA13 HSP90AA1 HTR2A HUWE1 MAP3K5 MAP3K7 MAPT OGT PPP2R1A PPP2R3A VHL
Entrez ID		1434	5536
HPRD ID		03217	02805
Ensembl ID		ENSG00000124207	ENSG00000011485
Uniprot IDs		A0A384NKW7 P55060	A0A024R0Q7 P53041
PDB IDs			1A17 1S95 1WAO 2BUG 3H60 3H61 3H62 3H63 3H64 3H66 3H67 3H68 3H69 4ZVZ 4ZX2 5HPE 5UI1 5WG8
Enriched GO Terms of Interacting Partners?
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