ZFP28 and PRKRA

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		ZFP28	PRKRA
Description		ZFP28 zinc finger protein	protein activator of interferon induced protein kinase EIF2AK2
Image
GO Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm RISC-loading Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding	RNA Binding Double-stranded RNA Binding Protein Binding Enzyme Activator Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Pre-miRNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Protein Phosphorylation Immune Response Negative Regulation Of Cell Population Proliferation Response To Virus Production Of SiRNA Involved In RNA Interference Pre-miRNA Processing Cellular Response To Oxidative Stress Production Of MiRNAs Involved In Gene Silencing By MiRNA Outer Ear Morphogenesis Middle Ear Morphogenesis Skeletal System Morphogenesis Regulation Of Catalytic Activity Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Generic Transcription Pathway	MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)	Inflammatory skin disease ( 25574825) Multiple sclerosis (OCB status) ( 23472185) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)
Interacting Genes		5 interacting genes: C8orf33 HMOX2 KDM1A PPP2CB PRKRA	34 interacting genes: ADARB1 AGO2 CAT CEBPZ CEP126 CLASP1 COPS6 DICER1 EHHADH EIF2AK2 FZD7 GDF9 HEYL LNX1 LYAR NKRF PIAS2 PITPNM1 PLEKHA3 POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 STAU1 STRBP TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZMAT4 ZNF746
Entrez ID		140612	8575
HPRD ID		15725	04573
Ensembl ID		ENSG00000196867	ENSG00000180228
Uniprot IDs		Q8NHY6	A0A7I2V2I8 B4DJC7 O75569
PDB IDs		2EM2 2EM3 2EM4 2EMJ 2EMK 2EML 2EN9 2ENH 2EOH 2EP0 2EPX 2EPZ 2YTM	2DIX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?