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UPRT and POLR2G
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
86
Data Source:
BioGRID
(two hybrid)
UPRT
POLR2G
Description
uracil phosphoribosyltransferase homolog
RNA polymerase II subunit G
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Intracellular Membrane-bounded Organelle
P-body
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
Molecular Function
Protein Binding
GTP Binding
Single-stranded DNA Binding
Single-stranded RNA Binding
DNA-directed 5'-3' RNA Polymerase Activity
Protein Binding
Translation Initiation Factor Binding
Biological Process
UMP Biosynthetic Process
Female Pregnancy
Lactation
Nucleoside Metabolic Process
Response To Insulin
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Apoptotic Process
Positive Regulation Of Translational Initiation
Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
9 interacting genes:
COMMD1
ERH
GGA3
HSF2BP
KAT5
NPM3
POLR2G
PPL
PYROXD1
47 interacting genes:
ATF7IP
BBS1
BCL2L15
C22orf15
CIB3
CNTNAP2
DDX54
DES
DUSP29
EIF3D
EIF4A3
EWSR1
FNDC4
FOSL2
GPKOW
HOXC5
KIF5B
LMO2
MAPK1
MCM3AP
MCPH1
MYOD1
NOTCH2NLA
NTRK2
OSGIN1
PARVG
POLR1C
POLR2A
POLR2C
POLR2D
POLR2E
POLR2F
POLR2H
POLR2K
POLR2L
PRKRA
PSMB8
STK19
TAF15
TNNC1
TRAPPC2L
TRIM14
TRIM68
TSEN15
UPRT
VHL
ZNF410
Entrez ID
139596
5436
HPRD ID
06640
15995
Ensembl ID
ENSG00000094841
ENSG00000168002
Uniprot IDs
A0A0A0MRR5
A8KAF9
Q96BW1
P62487
PDB IDs
2C35
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
Enriched GO Terms of Interacting Partners
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