MTPN and CAPZB

Number of citations of the paper that reports this interaction (PubMedID 12488317)
29

Data Source:
HPRD (in vivo)

		MTPN	CAPZB
Description		myotrophin	capping actin protein of muscle Z-line subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol F-actin Capping Protein Complex Axon Perinuclear Region Of Cytoplasm	Cytosol Cytoskeleton Brush Border F-actin Capping Protein Complex Postsynaptic Density Actin Cytoskeleton Membrane Sarcomere Lamellipodium Cortical Cytoskeleton Extracellular Exosome WASH Complex Sperm Connecting Piece Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse
	Molecular Function	Sequence-specific DNA Binding	Actin Binding Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Regulation Of Translation Catecholamine Metabolic Process Regulation Of Cell Size Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Striated Muscle Tissue Development Cerebellar Granule Cell Differentiation Neuron Differentiation Positive Regulation Of Cell Growth Skeletal Muscle Tissue Regeneration Positive Regulation Of NF-kappaB Transcription Factor Activity Striated Muscle Cell Differentiation Positive Regulation Of Protein Metabolic Process Cellular Response To Mechanical Stimulus Regulation Of Barbed-end Actin Filament Capping	Cell Morphogenesis Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Lamellipodium Assembly Regulation Of Cell Morphogenesis Lamellipodium Assembly Barbed-end Actin Filament Capping Negative Regulation Of Filopodium Assembly
Pathways			MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic RHOD GTPase cycle RHOF GTPase cycle Sensory processing of sound by inner hair cells of the cochlea Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Mean platelet volume ( 32888494) Platelet count ( 27863252) Platelet distribution width ( 32888494 27863252) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease and psoriasis ( 22482804) Heel bone mineral density ( 30598549) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Hyperthyroidism ( 30367059) Hypothyroidism ( 30367059 27182965) Lead levels in blood ( 25820613) Lung adenocarcinoma (survival time) in never smokers ( 32699080) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Serum thyroid-stimulating hormone levels ( 24852370) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997 25743335) Thyroid volume ( 21565293)
Interacting Genes		6 interacting genes: CAPZB ICAM1 MAPK1 NFKB1 REL RELA	9 interacting genes: BCCIP CDC42 HSPA8 MRPL20 MTPN PTN RPP14 SIRPA VHL
Entrez ID		136319	832
HPRD ID		07574	11872
Ensembl ID		ENSG00000105887	ENSG00000077549
Uniprot IDs		P58546 Q69YG1	A0A384MR50 B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0
PDB IDs		3AAA 7DF7 7DSA 7DSB
Enriched GO Terms of Interacting Partners?
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