CPD and CRYBA1

		CPD	CRYBA1
Description		carboxypeptidase D	crystallin beta A1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane Extracellular Exosome	Nucleus Cytoplasm
	Molecular Function	Metallocarboxypeptidase Activity Serine-type Carboxypeptidase Activity Zinc Ion Binding	Molecular_function Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Peptide Metabolic Process Protein Processing	Negative Regulation Of Cytokine Production Lens Development In Camera-type Eye Visual Perception Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of TOR Signaling Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Anoikis
Pathways		Golgi Associated Vesicle Biogenesis RND3 GTPase cycle RND1 GTPase cycle
Drugs		Guanidinoethylmercaptosuccinic acid
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mean reticulocyte volume ( 32888494) Night sleep phenotypes ( 27126917)
Interacting Genes		4 interacting genes: AATF CRYBA1 ECPAS PLIN3	33 interacting genes: ARID5A BANF2 CELF6 CERK CHCHD2 CPD CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 CYSRT1 EVI2A EVI2B FBXO3 FOXH1 HOXC8 KLK10 KRTAP11-1 KRTAP13-2 KRTAP13-3 LASP1 NF1 NOXA1 OMG PLEKHF2 PROP1 RBPMS RHOXF2 SPRR1B TAF15 VAC14 YPEL3
Entrez ID		1362	1411
HPRD ID		04375	00429
Ensembl ID		ENSG00000108582	ENSG00000108255
Uniprot IDs		O75976	P05813
PDB IDs		5AQ0
Enriched GO Terms of Interacting Partners?
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