TRIM50 and TSSK3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TRIM50	TSSK3
Description		tripartite motif containing 50	testis specific serine kinase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Protein Ubiquitination	Protein Phosphorylation Spermatogenesis Cell Differentiation Intracellular Signal Transduction
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-12p40) ( 22610502)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		40 interacting genes: ARHGAP45 CDK18 CLK2 EFHC2 EPM2AIP1 FAM221B GCC1 HDAC6 IQUB KLHL2 L3MBTL2 LNX1 MEOX2 PIAS2 PLA2G6 RAD23A RSPH14 SNAI1 SPG21 SRC TEPSIN TRAF2 TRIM27 TSGA10IP TSSK3 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2N UBTD1 USP2 XAF1 ZNF438 ZNF620	67 interacting genes: ADAMTSL4 ARID5A ATP23 C15orf48 C2CD6 C9orf24 CENPN DDIT4L DRG2 ECSIT EFHC2 EYA2 FUT9 GOLGA2 GP2 IKZF3 INCA1 KRT75 KRTAP13-2 KRTAP13-3 LBX1 LHX3 LMO2 LNX1 LZTS2 MBD3L1 MEI4 MRPL28 MSX2 MYOG MYOZ3 NFKBID NME4 OIP5 PBX4 PJA1 PLEKHG4 PPP1R16A PRDM6 RBBP4 RBCK1 REL RIN3 RUSC1 SHISA6 SLAIN1 SMAD4 STAT5B SYNGAP1 TCF4 TCP10L TEPSIN TGM7 TLE5 TRIM35 TRIM50 TRIM54 TRIM9 TRIP6 UROD USP54 VGLL1 VPS52 YJU2B YPEL3 ZBTB25 ZMYND12
Entrez ID		135892	81629
HPRD ID		15566	09635
Ensembl ID		ENSG00000146755	ENSG00000162526
Uniprot IDs		B7ZLG2 Q2M204 Q86XT4	Q96PN8
PDB IDs
Enriched GO Terms of Interacting Partners?
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