ZNF474 and NOXA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF474	NOXA1
Description		zinc finger protein 474	NADPH oxidase activator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol NADPH Oxidase Complex
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding
	Biological Process		Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst
Pathways			RHO GTPases Activate NADPH Oxidases CDC42 GTPase cycle RAC1 GTPase cycle RAC3 GTPase cycle WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998)	Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		29 interacting genes: ABI2 ATP6V0D2 BANP C2CD6 CABP5 CCDC57 COMMD8 CPNE7 CTNNA3 FRMD8 GPATCH11 GRB2 GYS1 IL16 KCTD7 MCMBP MLH1 NOXA1 PFKFB1 PPL PRKAB2 RSPH14 SEPHS1 TCF19 TEKT4 TRIM23 TSR2 UBASH3A ZIC1	57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620
Entrez ID		133923	10811
HPRD ID		13411	17644
Ensembl ID		ENSG00000164185	ENSG00000188747
Uniprot IDs		Q6S9Z5	Q86UR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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