LIN54 and ZNF76

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LIN54	ZNF76
Description		lin-54 DREAM MuvB core complex component	zinc finger protein 76
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	Transcription Regulatory Region Nucleic Acid Binding Minor Groove Of Adenine-thymine-rich DNA Binding Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Cell Cycle Nucleosome Positioning	Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 30224653 30578418) Red blood cell count ( 29403010 32888494 27863252) Red cell distribution width ( 32888494) Systolic blood pressure ( 30578418) White blood cell count ( 32888494)	Height ( 25282103 31562340 18391951) Plateletcrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: BANP NFYC RB1 SF3A2 SP3 ZNF143 ZNF76	95 interacting genes: ACAT2 ADD3 ALOXE3 ANKRD37 ANTKMT ATP5PO BLZF1 BOLA2 BOLA2B C10orf55 C22orf15 C3orf36 CCDC33 CEACAM6 CEP76 CSN3 CSNK2B DDIT4L DISC1 ENKD1 EP300 EXOSC1 FAM228A FAM90A1 FCRL4 FHL2 FNDC8 FSD2 GIMAP6 GRAPL HDAC1 HOMEZ IKZF3 KCTD9 KLF15 KPNA3 KRT40 KRT75 L3MBTL3 LAP3 LETM1 LHX3 LHX4 LHX6 LIN37 LIN54 LMO1 MAGEA6 MBD3L1 MBD5 MED19 MFAP1 MORN3 MRPL12 MTFR1L MTUS2 MYL10 NEDD9 NRIP2 PIAS1 PMPCA POGZ PRKAR1B RAB3IP RALY REL RNF214 RPRD1A RPS21 SCNM1 SLAIN1 SMAD1 SNAI2 SPANXN3 SPATA8 STMN3 TASOR2 TBC1D22B TBP TEKT5 TEX43 TGS1 TNNI1 USP54 USP6 USP7 VXN WDR83 YPEL3 ZC2HC1C ZC4H2 ZMYM6 ZNF420 ZNF526 ZNF623
Entrez ID		132660	7629
HPRD ID		13218	01929
Ensembl ID		ENSG00000189308	ENSG00000065029
Uniprot IDs		Q6MZP7 Q7Z3G2	A0A024RCU3 A0A024RCW5 P36508
PDB IDs		5FD3
Enriched GO Terms of Interacting Partners?
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