COPB1 and GTPBP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		COPB1	GTPBP4
Description		COPI coat complex subunit beta 1	GTP binding protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane COPI Vesicle Coat Transport Vesicle Secretory Granule Membrane Intracellular Membrane-bounded Organelle Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Structural Molecule Activity Protein Binding	RNA Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Osteoblast Differentiation Negative Regulation Of DNA Replication Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell-cell Adhesion Negative Regulation Of Cell Migration Negative Regulation Of Protein Ubiquitination Negative Regulation Of Collagen Binding Protein Stabilization
Pathways		Neutrophil degranulation COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		HDL cholesterol ( 26780889) HDL cholesterol levels ( 32203549 28334899) Height ( 31562340) High chromosomal aberration frequency (total) ( 31586183) Hip circumference adjusted for BMI ( 34021172) Vitamin D levels ( 25208829)	Height ( 28552196)
Interacting Genes		44 interacting genes: ADAM19 APP ARCN1 ARF1 BCAR1 COPE COPG1 COPG2 ERBIN FOXB1 GORAB GRB2 GTPBP4 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 KIAA1328 LINC00839 LZTS1 LZTS2 NUB1 PDGFRB PRKCE PTEN RGS2 RGS4 RHOQ SCYL1 SERTAD1 SNTA1 SPTBN1 TANK TAPBP TMED10 TRIM37 TTYH2 UBC UBQLN4 VPS18 WBP2 XRCC6	6 interacting genes: COPB1 IL2RA PRKN PTGFR SRPK2 YWHAG
Entrez ID		1315	23560
HPRD ID		02981	09976
Ensembl ID		ENSG00000129083	ENSG00000107937
Uniprot IDs		P53618	D2CFK9 Q9BZE4
PDB IDs			6LSS 6LU8
Enriched GO Terms of Interacting Partners?
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