KLHL40 and ZNF451

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KLHL40	ZNF451
Description		kelch like family member 40	zinc finger protein 451
Image
GO Annotations	Cellular Component	Cytoplasm Cul3-RING Ubiquitin Ligase Complex A Band I Band	Nucleus PML Body
	Molecular Function	Protein Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding SUMO Ligase Activity
	Biological Process	Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Skeletal Muscle Fiber Development Skeletal Muscle Fiber Differentiation	Regulation Of Gene Expression Protein Sumoylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Histone H3-K9 Acetylation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		13 interacting genes: AHNAK C7orf31 CC2D1B FSD2 LMOD3 LRRC29 MCM10 REL SAXO1 TASOR2 VDAC1 ZBED1 ZNF451	34 interacting genes: AR CALCOCO2 CDC5L CDCA4 CPTP CREB1 CREBBP FAM118A FXR2 HTT JMJD6 KDM1A KLHL40 LZTR1 MID2 OPLAH PCBD1 PIAS1 PIAS2 PIK3R3 PML PRMT1 PRMT8 PRPF40A RAP1GDS1 RNF40 SNIP1 SUMO1 SUMO2 SUV39H1 UBC UBE2I ZBED1 ZNF467
Entrez ID		131377	26036
HPRD ID		11058	10332
Ensembl ID		ENSG00000157119	ENSG00000112200
Uniprot IDs		A8K5H9 Q2TBA0	B4DYS2 Q96JY2 Q9Y4E5
PDB IDs		4ASC	5D2M
Enriched GO Terms of Interacting Partners?
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