CPNE4 and PITPNM2

Number of citations of the paper that reports this interaction (PubMedID 12522145)
38

Data Source:
HPRD (in vitro, two hybrid)

		CPNE4	PITPNM2
Description		copine 4	phosphatidylinositol transfer protein membrane associated 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Extracellular Exosome	Cytoplasm Cytosol Endomembrane System Membrane Cell Body
	Molecular Function	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding	Calcium Ion Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Receptor Tyrosine Kinase Binding Phosphatidylcholine Binding Phosphatidylinositol Binding
	Biological Process	Cellular Response To Calcium Ion	Phosphatidylinositol Biosynthetic Process Phospholipid Transport Phosphatidylinositol-mediated Signaling Intermembrane Lipid Transfer
Pathways			Synthesis of PI
Drugs
Diseases
GWAS		Adult body size ( 32376654) Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Amyotrophic lateral sclerosis ( 22959728) Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728) Body mass index ( 31453325 28892062 25673413) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Circulating leptin levels in high cardiovascular risk ( 31766143) Coronary artery aneurysm in Kawasaki disease ( 27171184) HDL cholesterol levels ( 32203549) Intracranial aneurysm ( 29531279) Iron status biomarkers (total iron binding capacity) ( 28334935) Metabolic syndrome ( 31589552) Motion sickness ( 25628336) Neutrophil count ( 21507922) Retinitis pigmentosa ( 33514863)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 32296059) Asthma (childhood onset) ( 30929738) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Educational attainment ( 25201988) Eosinophil percentage of white cells ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172 25673412) Hip index ( 34021172) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Macular thickness ( 30535121) Mean platelet volume ( 27863252) Menopause (age at onset) ( 26414677) Multiple sclerosis ( 31604244 24076602) Platelet count ( 21507922) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 25056061 29483656 23974872) Tourette syndrome ( 30818990) Type 2 diabetes ( 30054458) Uterine fibroids ( 31649266) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		18 interacting genes: ACAD11 ACTB BCOR BICD1 CCDC22 CEP162 CPNE1 MAP2K1 MYCBP NECAB1 PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 UBE2M UBE2O	3 interacting genes: CPNE1 CPNE4 PTK2B
Entrez ID		131034	57605
HPRD ID		05017	08335
Ensembl ID		ENSG00000196353	ENSG00000090975
Uniprot IDs		B7Z370 Q4G168 Q96A23	Q9BZ72 Q9UF51
PDB IDs
Enriched GO Terms of Interacting Partners?
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