COL6A1 and LGALS3BP

Number of citations of the paper that reports this interaction (PubMedID 9501082)
59

Data Source:
HPRD (in vitro, in vivo)

		COL6A1	LGALS3BP
Description		collagen type VI alpha 1 chain	galectin 3 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type VI Trimer Extracellular Space Lysosomal Membrane Endoplasmic Reticulum Lumen Membrane Protein-containing Complex Sarcolemma Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Space Membrane Platelet Dense Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Collagen Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Platelet-derived Growth Factor Binding	Scavenger Receptor Activity Protein Binding
	Biological Process	Osteoblast Differentiation Cell Adhesion Endodermal Cell Differentiation Cellular Response To Amino Acid Stimulus	Endocytosis Cellular Defense Response Cell Adhesion Signal Transduction
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans ECM proteoglycans NCAM1 interactions Collagen chain trimerization	Platelet degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Bone mineral density (lumbar spine) in inflammatory bowel disease ( 29603369) Corneal hysteresis ( 32716492 30894546) Corneal resistance factor ( 31246245 32716492 30894546) Daytime nap ( 33568662) Diverticular disease ( 30177863) Intraocular pressure ( 29617998 29235454) Keratoconus ( 33649486) Myopia ( 27182965) Pulse pressure ( 30224653 30578418) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 28234671) Waist circumference adjusted for body mass index ( 34021172 25673412)	Blood protein levels ( 30072576)
Interacting Genes		24 interacting genes: ALDH3A2 CFAP410 COL2A1 COL6A2 CSTB DCN DNAJB11 FAM3B FGF7 HCFC2 LAMB1 LCMT2 LGALS3BP MAG MLLT3 MPRIP MTDH PCNT PDGFA PDGFB PDK1 PEX26 PIGS RUNX1	24 interacting genes: CD14 COL5A1 COL6A1 FBXO7 FN1 GALNT6 HSP90AA1 ITGA5 ITGA6 ITGAV ITGB1 LGALS1 LGALS3 NID1 PPIC SELE SIGLEC10 SIGLEC11 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC9 WNT4 XRN1
Entrez ID		1291	3959
HPRD ID		00370	02796
Ensembl ID		ENSG00000142156	ENSG00000108679
Uniprot IDs		A0A384P5H7 P12109	A0A0S2Z3Y1 Q08380
PDB IDs			1BY2 6GFB
Enriched GO Terms of Interacting Partners?
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