SNX20 and NFATC3

		SNX20	NFATC3
Description		sorting nexin 20	nuclear factor of activated T cells 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Early Endosome Membrane	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Phosphate Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Transport	Cytokine Production Regulation Of Transcription By RNA Polymerase II Inflammatory Response Calcineurin-NFAT Signaling Cascade Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Pathways			Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization CLEC7A (Dectin-1) induces NFAT activation
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 31036433) Crohn's disease ( 28008999 28067908 22412388) Inflammatory bowel disease ( 28008999 28067908)	Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462) Fasting glucose ( 33402679) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Serum alkaline phosphatase levels ( 33547301) Urate levels ( 31578528)
Interacting Genes		9 interacting genes: ALAS1 FAM9B GMCL1 KLHL12 MAGEA11 NFATC3 SPDEF TACC3 TFIP11	13 interacting genes: CALB2 CDK6 CELSR2 CSNK1A1 FOS KCNJ3 MAPK8 MAPK9 MYOCD SEC24A SNX20 TOR1B TTF1
Entrez ID		124460	4775
HPRD ID		15401	04077
Ensembl ID		ENSG00000167208	ENSG00000072736
Uniprot IDs		Q7Z614	B5B2S0 B5B2S1 Q12968
PDB IDs			2XRW 2XS0
Enriched GO Terms of Interacting Partners?
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