NOXO1 and NOXA1

Number of citations of the paper that reports this interaction (PubMedID 12716910)
94

Data Source:
HPRD (two hybrid, in vivo)

		NOXO1	NOXA1
Description		NADPH oxidase organizer 1	NADPH oxidase activator 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane NADPH Oxidase Complex	Cytosol NADPH Oxidase Complex
	Molecular Function	Protein Binding Phospholipid Binding Superoxide-generating NADPH Oxidase Activator Activity Enzyme Binding Phosphatidylinositol Binding	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding
	Biological Process	Regulation Of Hydrogen Peroxide Metabolic Process Extracellular Matrix Disassembly Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Catalytic Activity Regulation Of Respiratory Burst
Pathways		RHO GTPases Activate NADPH Oxidases CDC42 GTPase cycle RAC1 GTPase cycle RAC3 GTPase cycle WNT5:FZD7-mediated leishmania damping	RHO GTPases Activate NADPH Oxidases CDC42 GTPase cycle RAC1 GTPase cycle RAC3 GTPase cycle WNT5:FZD7-mediated leishmania damping
Drugs		Ecabet
Diseases
GWAS		Red cell distribution width ( 32888494)	Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		2 interacting genes: NOX1 NOXA1	57 interacting genes: ANKRD55 C19orf54 C9orf24 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620
Entrez ID		124056	10811
HPRD ID		14834	17644
Ensembl ID		ENSG00000196408	ENSG00000188747
Uniprot IDs		A8K832 Q8NFA2	Q86UR1
PDB IDs		2L73
Enriched GO Terms of Interacting Partners?
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