CLK1 and KRTAP10-7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		CLK1	KRTAP10-7
Description		CDC like kinase 1	keratin associated protein 10-7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol Keratin Filament
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Protein Binding Identical Protein Binding
	Biological Process	Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation
Pathways			Keratinization
Drugs		Debromohymenialdisine CHGN111 ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate Fostamatinib
Diseases
GWAS		Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Triptolide cytotoxicity ( 26121980)
Interacting Genes		167 interacting genes: ABCA13 ACOX2 ANKFY1 ARHGEF12 ARPC4 ASL ASXL3 ATP10A ATP4A BCLAF1 BCS1L C1orf94 CDCP1 CDH23 CDK12 CELSR3 CENPE CEP95 CFAP20DC CFAP251 CKAP5 CLASRP CLK2 COCH CRNKL1 CTLA4 CTNND2 CUL3 CWC27 CYP46A1 DBR1 DENND4A DNAJC13 DNAJC24 DOCK9 DPYD DSC2 DVL3 ECE1 ELP6 ENO1 ERFE FAM189A1 FAT1 FBF1 FHIP2B GEMIN5 GOLM1 GRM6 GSDMB H2BC12 HADH HIVEP1 HNMT HNRNPA0 HNRNPA1 HNRNPA3 HSP90AB2P HSPBP1 HTATSF1 ICE1 IMPDH2 IP6K1 ITGA5 KATNA1 KHDRBS1 KIF14 KIF23 KRT8 KRTAP10-6 KRTAP10-7 LINS1 LMNA LNX1 LUC7L3 MAP3K21 MAP7 MBP MFHAS1 MFSD10 MICU3 MKRN2 MTBP MTCL1 MYOM1 NCL NCOR1 NF1 NPM1 NUP153 PATZ1 PDE9A PHF3 PHLDB2 PIAS4 PIP4K2B PKD1L1 PLAAT5 PLXDC2 PPFIBP2 PPHLN1 PPIG PPP1CB PRDX5 PRKDC PRMT5 PRPF38A PRPF4 PRPF4B PTPN1 PTPN22 RAD21L1 RAPH1 RASL12 RBBP6 RBM15 RBMX REV1 RLF RPL5 RPS4Y1 RPUSD3 SAFB SAMD9L SCARA3 SERPINI2 SF3B1 SFMBT2 SH2B2 SHROOM1 SLC35D3 SLFN5 SPEN SPTBN4 SRPK1 SRPK2 SRRM1 SRRM2 SRRM4 SRSF1 SRSF10 SRSF3 SRSF5 SRSF6 SRSF7 SSBP3 STIP1 STK31 SVOP TEX11 THRAP3 THY1 TJP2 TLN2 TMPO TMPRSS2 TNIP2 TP53RK TRA2B UBL5 UNC13B VWA7 YTHDC1 YWHAG ZC3H13 ZMYND10 ZNF148	282 interacting genes: AEN ALDH3B1 ANKRD36BP1 AP1M1 APP AQP1 AVPI1 B4GALT7 BAHD1 BCL6B BMP7 BRME1 BUD31 BYSL C8orf33 CARHSP1 CATIP CBX2 CCDC185 CCDC26 CCNG1 CDCA7L CHIC2 CHRD CHRNG CLK1 CLK4 CNNM3 COL8A1 CRCT1 CREB5 CRY2 CSNK1G1 CSNK1G2 CTNNBIP1 CTRC CXCL16 CYSRT1 DAAM2 DERL2 DHX57 DMRT3 DOCK2 E2F6 E4F1 EHHADH FADS6 FAM124B FAM161A FAM27E3 FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GEM GLIDR GLP1R GNE GOLGA8EP GRN GSTP1 GUCD1 HBZ HCK HHEX HOXA1 HOXC8 HPCAL1 HSBP1 HSD3B7 IGSF8 ING5 INPP5D IQUB ITGB4 ITGB5 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP26-1 KRTAP4-2 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1F LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LIMS2 LINC00242 LMNA LMO2 LRCH4 MAPKBP1 MCM5 MCRS1 MOBP MRGBP MXD3 MXI1 MYPOP NAA10 NAXD NECTIN2 NECTIN3 NKD1 NOL12 NOTCH2NLA NPBWR2 NPDC1 NTAQ1 NUBP2 NUDCD3 NUFIP2 OTX1 P2RY6 PCED1A PCSK5 PDE9A PDIA5 PDLIM5 PFKL PGAP6 PHLDA1 PIN1 POLL POM121L8P PPARD PRKAB2 PRM2 PRR13 PRR35 PTGDS PTGER3 PTPMT1 PVR R3HDM2 RNF175 RPF1 RPL11 RPL36AL RPS28 RPUSD3 RSPO2 RTN4RL1 RWDD2B SCNM1 SDCBP SHFL SLC23A1 SLC25A48 SLC6A20 SMCO4 SMCP SPACA9 SPATA24 SPATA3 SPATA8 SPG7 SPRY1 SSX2IP STAT3 STK16 SUV39H1 TAPBPL TCEA2 TCEANC TEDC2 TFAP2D THAP1 THAP6 TLE5 TMA16 TNP2 TNS2 TOR1A TREX1 TRIM42 TTPA TULP3 TXNDC5 TYRO3 UCP2 UXT VASN VGLL3 VTI1B WNT11 WT1 ZBTB24 ZBTB38 ZBTB48 ZBTB9 ZFP41 ZFYVE26 ZIM2 ZNF101 ZNF124 ZNF133 ZNF138 ZNF155 ZNF165 ZNF169 ZNF175 ZNF180 ZNF2 ZNF20 ZNF223 ZNF250 ZNF256 ZNF26 ZNF260 ZNF264 ZNF266 ZNF32 ZNF320 ZNF329 ZNF337 ZNF408 ZNF41 ZNF414 ZNF417 ZNF418 ZNF419 ZNF420 ZNF425 ZNF433 ZNF439 ZNF440 ZNF444 ZNF490 ZNF491 ZNF524 ZNF543 ZNF555 ZNF564 ZNF572 ZNF575 ZNF578 ZNF580 ZNF581 ZNF587 ZNF625 ZNF667 ZNF670 ZNF696 ZNF697 ZNF707 ZNF764 ZNF774 ZNF778 ZNF786 ZNF792 ZNF837 ZNF844 ZNF846 ZNHIT1 ZSCAN10 ZSCAN21 ZSCAN26
Entrez ID		1195	386675
HPRD ID		09058	11193
Ensembl ID		ENSG00000013441	ENSG00000272804
Uniprot IDs		P49759	P60409
PDB IDs		1Z57 2VAG 5J1V 5J1W 5X8I 6FT8 6FT9 6FYO 6G33 6I5H 6I5I 6I5K 6I5L 6KHD 6Q8K 6Q8P 6QTY 6R3D 6R6E 6R6X 6R8J 6RAA 6TW2 6YTA 6YTD 6YTE 6YTG 6YTI 6Z4Z 6Z50 6ZLN 7AK3
Enriched GO Terms of Interacting Partners?
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