ADD2 and BRWD1

		ADD2	BRWD1
Description		adducin 2	bromodomain and WD repeat domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane F-actin Capping Protein Complex Postsynaptic Density Cytoplasmic Vesicle Plasma Membrane Raft	Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Calmodulin Binding Protein Kinase Binding Spectrin Binding Protein Homodimerization Activity Protein Heterodimerization Activity Actin Filament Binding	Molecular_function
	Biological Process	Synapse Assembly Actin Cytoskeleton Organization Hemopoiesis Positive Regulation Of Protein Binding Leukocyte Migration Leukocyte Tethering Or Rolling Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Protein-containing Complex Assembly	Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Regulation Of Cell Shape
Pathways		Miscellaneous transport and binding events	Interleukin-7 signaling Interleukin-7 signaling Chromatin modifying enzymes
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Response to esketamine in treatment resistant depression ( 32724131)	Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Alanine aminotransferase levels ( 33547301) Apolipoprotein B levels ( 32203549) Cognitive function ( 25644384) Daytime nap ( 33568662) Daytime sleep phenotypes ( 27126917) General cognitive ability ( 29844566) LDL cholesterol ( 30275531) Liver enzyme levels (alanine transaminase) ( 33972514) Menarche (age at onset) ( 25231870) Platelet distribution width ( 32888494) Smoking initiation ( 33082346) Temperament (bipolar disorder) ( 22365631) Total cholesterol levels ( 30275531)
Interacting Genes		9 interacting genes: ADD1 APP BRWD1 CALM1 FYN PRKACA PRKCD PTPRZ1 RPH3A	15 interacting genes: ADD2 APP APPL1 CALM1 CUL4B EIF4E FNDC3B HDAC7 NRF1 NUTF2 SMARCA4 SMARCD1 STAT3 TRIM55 TRIM63
Entrez ID		119	54014
HPRD ID		00037	11683
Ensembl ID		ENSG00000075340	ENSG00000185658
Uniprot IDs		P35612 Q05DK5	Q9NSI6
PDB IDs			3Q2E
Enriched GO Terms of Interacting Partners?
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