ZFYVE27 and TSPAN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZFYVE27	TSPAN2
Description		zinc finger FYVE-type containing 27	tetraspanin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Cytosol Integral Component Of Endoplasmic Reticulum Membrane Axon Dendrite Growth Cone Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Endoplasmic Reticulum Tubular Network	Nucleoplasm Integral Component Of Plasma Membrane Integral Component Of Membrane Myelin Sheath
	Molecular Function	Protein Binding Identical Protein Binding Protein Self-association Metal Ion Binding	Protein Binding
	Biological Process	Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Axon Extension Neurotrophin TRK Receptor Signaling Pathway Endoplasmic Reticulum Tubular Network Formation Protein Localization To Plasma Membrane	Inflammatory Response Brain Development Astrocyte Development Microglia Development Myelination Oligodendrocyte Differentiation Axon Development
Pathways
Drugs
Diseases
GWAS			Dysmenorrheic pain ( 27454463) Ischemic stroke (large artery atherosclerosis) ( 26708676 29531354) Large artery stroke (CCS and TOAST classification) ( 32047268) Large artery stroke (CCS or TOAST classification) ( 32047268) Large artery stroke (CCSp classification)j ( 32047268) Migraine ( 27182965 23793025 27322543) Migraine without aura ( 23793025 27322543)
Interacting Genes		18 interacting genes: APP GIMAP1 GIMAP5 IER3IP1 ORMDL1 OTOP3 PIP4P2 SACM1L SEC22A SLC30A8 SLC66A2 STX7 TMEM128 TMEM14C TMEM243 TMEM65 TSPAN2 YIF1A	36 interacting genes: ABHD16A ATP1B4 BSCL2 CD79A CLDN5 CLEC14A CREB3 CREB3L1 DCBLD2 FAM209A FKBP7 FOS GRB2 IFNGR2 KDELR3 LEPROTL1 LMNA MFF MGST3 MOV10 PGRMC2 PIK3R3 RABGAP1L REEP4 RNF19B SCN3B SLC10A6 SLC30A8 SLC35C2 TMEM130 TMEM14B TMEM31 TMX2 TSPAN31 VSIR ZFYVE27
Entrez ID		118813	10100
HPRD ID		15735	18233
Ensembl ID		ENSG00000155256	ENSG00000134198
Uniprot IDs		A0A0S2Z627 B7Z6J9 Q5T4F4	B1AKP1 B2RD31 O60636
PDB IDs		1X4U
Enriched GO Terms of Interacting Partners?
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