RAB3IP and RAB8B

Number of citations of the paper that reports this interaction (PubMedID 12221131)
84

Data Source:
HPRD (two hybrid)

		RAB3IP	RAB8B
Description		RAB3A interacting protein	RAB8B, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Microtubule Organizing Center Cytosol Lamellipodium Golgi To Plasma Membrane Transport Vesicle	Nucleoplasm Endosome Peroxisomal Membrane Plasma Membrane Synaptic Vesicle Nuclear Body Trans-Golgi Network Transport Vesicle Phagocytic Vesicle Membrane Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Cell Tip Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding GDP Binding TPR Domain Binding
	Biological Process	Protein Targeting To Membrane Exocytosis Regulation Of Catalytic Activity Cilium Assembly Ciliary Basal Body-plasma Membrane Docking	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Cell Projection Organization Cellular Response To Insulin Stimulus Protein Import Into Peroxisome Membrane Golgi Vesicle Fusion To Target Membrane Positive Regulation Of Corticotropin Secretion Cilium Assembly Protein Localization To Plasma Membrane Cell-substrate Junction Organization
Pathways		Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs	TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs			Phosphoaminophosphonic acid guanylate ester Guanosine-5'-Diphosphate
Diseases
GWAS		Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)	Refractive error ( 32231278) Serum metabolite levels ( 23093944) Social communication problems ( 24564958)
Interacting Genes		33 interacting genes: BANP CCDC196 CHCHD3 DNAJB13 FAM124A GPD2 KRT40 MB21D2 MBD3 MVP NAA10 PEG10 PKN1 PLOD3 PPL PRKAB2 RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TBC1D21 TEPSIN TRAPPC6A TXNDC5 ZBTB16 ZNF410 ZNF76	8 interacting genes: APP CDH1 RAB3IP RALA TUBA4A TUBB VIM VPS13C
Entrez ID		117177	51762
HPRD ID		10565	11476
Ensembl ID		ENSG00000127328	ENSG00000166128
Uniprot IDs		Q96QF0	Q92930
PDB IDs		4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P
Enriched GO Terms of Interacting Partners?
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