CKS1B and MED12L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CKS1B	MED12L
Description		CDC28 protein kinase regulatory subunit 1B	mediator complex subunit 12L
Image			No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleoplasm SCF Ubiquitin Ligase Complex	Mediator Complex
	Molecular Function	Protein Binding Protein Kinase Binding Histone Binding Ubiquitin Binding Cyclin-dependent Protein Serine/threonine Kinase Activator Activity	Transcription Coactivator Activity Protein Binding Beta-catenin Binding
	Biological Process	Cell Cycle Regulation Of Mitotic Cell Cycle Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated
Pathways		SCF(Skp2)-mediated degradation of p27/p21 Cyclin D associated events in G1
Drugs		Fluoxetine 2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Prostate cancer ( 23535732)	Chronotype ( 30696823) Eosinophil counts ( 32888494) Epstein-Barr virus EBNA-1 antibody levels ( 33204752) Heschl's gyrus morphology ( 25130324) Lymphocyte counts ( 32888494) Parkinson's disease ( 32201043) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Trunk fat mass ( 28552196) White blood cell count ( 32888494)
Interacting Genes		60 interacting genes: AP2M1 ARID5A CBY2 CCDC120 CCNA1 CCNB2 CCNC CDC27 CDC37 CDK2 CDK3 CDKN1B CDX4 CKS1BP7 CKS2 CT45A1 CUL1 DCDC2 DUSP1 ECPAS GAS8 HSF2BP HSP90AA1 IKZF1 IKZF3 INCA1 KPRP KRTAP10-9 KRTAP5-9 LDHB LHX3 LZTS1 MED12L MEOX1 MEOX2 MIPOL1 NR5A1 PAX5 PAX6 PPP1R13B PSMD9 REL ROPN1 SEPTIN3 SERTAD1 SERTAD2 SKP2 SNRNP35 SPDYE4 SSBP1 SUMO1P1 TCF12 TCF4 TRIM14 TRIM27 TRIM49 TRIM49C WASF3 XIAP ZBTB9	8 interacting genes: AR CKS1B IGSF10 LAMTOR5 MAPK9 MSRB3 TLE5 TTC23
Entrez ID		1163	116931
HPRD ID		00299	10278
Ensembl ID		ENSG00000173207	ENSG00000144893
Uniprot IDs		P61024 Q5T178	B3KXY0 Q86YW9
PDB IDs		1BUH 1DKS 1DKT 2ASS 2AST 4YC6 7B5L 7B5M 7B5R
Enriched GO Terms of Interacting Partners?
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