FCHO2 and MRPS27

		FCHO2	MRPS27
Description		FCH and mu domain containing endocytic adaptor 2	mitochondrial ribosomal protein S27
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle Presynaptic Endocytic Zone Membrane	Nucleolus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol Binding Identical Protein Binding	TRNA Binding Protein Binding RRNA Binding Mitochondrial Ribosome Binding
	Biological Process	Membrane Invagination Clathrin Coat Assembly Synaptic Vesicle Endocytosis Clathrin-dependent Endocytosis Protein Localization To Plasma Membrane	Cell Population Proliferation Positive Regulation Of Mitochondrial Translation
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
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Diseases
GWAS		Albumin-globulin ratio ( 29403010) Aspartate aminotransferase levels ( 33547301 29403010 33339817) Discordance in emotional problems in monozygotic twins ( 27043157) Eyebrow thickness ( 26926045) Factor VIII levels ( 30586737) Heel bone mineral density ( 30598549) Immunoglobulin measurement (zinc sulfate turbidity test) ( 29403010) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin concentration ( 32888494) Mean platelet volume ( 32888494) Monobrow thickness ( 26926045) Non-albumin protein levels ( 29403010) Red cell distribution width ( 32888494 27863252) Serum albumin level ( 29403010) Small cell lung carcinoma ( 28604730) vWF levels ( 30586737) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549)	Refractive error ( 32231278)
Interacting Genes		7 interacting genes: DAB2 EPS15 EPS15L1 ITSN1 MRPS27 RHOU UBC	5 interacting genes: CARTPT FCHO2 NECAB2 PTEN YWHAQ
Entrez ID		115548	23107
HPRD ID		13319	17596
Ensembl ID		ENSG00000157107	ENSG00000113048
Uniprot IDs		Q0JRZ9	A0A024RAJ1 G5EA06 Q6PKB3 Q92552
PDB IDs		2V0O	3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K
Enriched GO Terms of Interacting Partners?
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