PNMA5 and ARPC4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PNMA5	ARPC4
Description		PNMA family member 5	actin related protein 2/3 complex subunit 4
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytosol Arp2/3 Protein Complex Site Of Double-strand Break Cell Projection Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Enzyme Binding Protein-macromolecule Adaptor Activity Actin Filament Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Actin Filament Polymerization Arp2/3 Complex-mediated Actin Nucleation Actin Nucleation
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs			N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS
Interacting Genes		59 interacting genes: AP1M1 APPL1 ARPC4 BHLHB9 C11orf49 CADPS CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 CRACR2A CTNNA3 DDX6 DZIP1L EHHADH FOXH1 FSD2 GAS8 GLIPR2 GOLGA6L9 GORASP2 GRB2 GYS1 HOOK3 HSF2BP KIF9 KIFC3 KPNA2 LHX3 LNX1 MAGED1 MOAP1 MYO15B NTAQ1 PAX5 PNKP PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 SORBS3 SPG21 TBC1D22B TCEA2 TCEANC TNPO2 TTC23 TXNL4B UBASH3A VIM VPS28 ZBTB25 ZFYVE26 ZMYND19 ZRANB1	13 interacting genes: ACTR2 ACTR3 ARPC1B ARPC2 ARPC3 ARPC5 ARPC5L CLK1 METTL21A NELFCD PNMA5 RNF130 WASL
Entrez ID		114824	10093
HPRD ID		06678	10368
Ensembl ID		ENSG00000198883	ENSG00000241553
Uniprot IDs		Q96PV4	P59998
PDB IDs			6UHC 6YW6 6YW7
Enriched GO Terms of Interacting Partners?
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