DTX2 and UBE2D4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid, affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		DTX2	UBE2D4
Description		deltex E3 ubiquitin ligase 2	ubiquitin conjugating enzyme E2 D4 (putative)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Nuclear Membrane	Ubiquitin Ligase Complex Nucleus
	Molecular Function	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Notch Signaling Pathway Protein Ubiquitination	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways		Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		132 interacting genes: ABHD11 ABHD16A ALKBH4 ANAPC11 ANTKMT ARID5A ARMC7 ARNT2 BCL2L11 BICRAL BOLA2-SMG1P6 C10orf55 C11orf1 C19orf54 C1orf94 C20orf85 C22orf39 CCDC57 CLPP COA6 COQ8A DAZAP2 DOK3 DTX1 DTX3 ECM1 ECSIT EIF4ENIF1 EIF4G1 EYA2 FAM168A FCRL4 FHL2 FHL5 FOXI1 FTO GLYCTK GOLGA2 H3C1 HDC HGS HLX HOXA1 HOXB2 HOXD12 HPCA HPCAL1 HPCAL4 HSFY1 HSFY2 IKZF3 KANK2 KLC3 KLHDC7B KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP7-1 KRTAP8-1 LASP1 LNX1 LRP2BP MBD3L1 MDC1 MED19 MSS51 MVP MXRA8 NCALD NCS1 NHLRC4 NIF3L1 NME4 NOTCH1 OIP5 PARP1 PAX5 PLEKHF2 PLEKHG4 PLSCR1 POGZ PPP1R32 PRR32 PRR34 PSMB4 QARS1 RBM11 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 RUSC1 SEC22A SEC23A SEC23B SEPSECS SLC22A18AS SOHLH1 SPAG8 SPG21 STX12 SUMO1 TBX15 TEKT5 TENT2 TMEM42 TRIB3 TRIM35 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBQLN4 USP54 VGLL3 VSNL1 ZNF34 ZNF503 ZNF620 ZNF641 ZNF764 ZNF774 ZNF85	107 interacting genes: AMFR ARIH2 BFAR BIRC8 CADPS2 CHFR CNOT4 DAZAP2 DTX1 DTX2 DTX3 DTX3L DZIP3 IKBKG INCA1 ITCH LNX1 LRSAM1 MAGEA11 MAP3K1 MARCHF3 MDM2 MGRN1 MIB1 MID1 MID2 MKRN1 MKRN2 MKRN3 MUL1 MYBL2 MYLIP OTUB1 PHF7 PJA2 POLR2E PRKN RBCK1 RCHY1 REL RFWD3 RING1 RLIM RMND5B RNF10 RNF103 RNF11 RNF111 RNF114 RNF115 RNF125 RNF126 RNF13 RNF130 RNF138 RNF14 RNF150 RNF165 RNF166 RNF167 RNF181 RNF185 RNF2 RNF216 RNF26 RNF31 RNF38 RNF4 RNF43 RNF5 RNF7 SIAH1 STUB1 TOPORS TRAF6 TRAF7 TRIM10 TRIM17 TRIM2 TRIM23 TRIM25 TRIM27 TRIM3 TRIM31 TRIM35 TRIM38 TRIM39 TRIM43 TRIM45 TRIM5 TRIM50 TRIM54 TRIM62 TRIM8 UBA1 UBC UBE4A UBOX5 UBTD1 UBTD2 UFM1 UHRF2 UVSSA XIAP ZNRF1 ZNRF2 ZNRF4
Entrez ID		113878	51619
HPRD ID		16841	14242
Ensembl ID		ENSG00000091073	ENSG00000078967
Uniprot IDs		Q86UW9	A0A024RA90 Q9UQL0 Q9Y2X8
PDB IDs		6IR0 6Y22 6Y2X 6Y3J
Enriched GO Terms of Interacting Partners?
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