TWF2 and CHGB

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TWF2	CHGB
Description		twinfilin actin binding protein 2	chromogranin B
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Actin Filament Myofibril Lamellipodium Filopodium Growth Cone Stereocilium Perinuclear Region Of Cytoplasm Extracellular Exosome	Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule
	Molecular Function	RNA Binding Actin Monomer Binding Protein Kinase C Binding Protein Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Cadherin Binding Actin Filament Binding	Hormone Activity Protein Binding
	Biological Process	Regulation Of Lamellipodium Assembly Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Cell Projection Organization Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Regulation Of Microvillus Length Regulation Of Actin Cytoskeleton Organization Sequestering Of Actin Monomers Positive Regulation Of Axon Extension Barbed-end Actin Filament Capping Cellular Response To Retinoic Acid Cellular Response To Growth Factor Stimulus	Signal Transduction
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Schizophrenia ( 23974872)	Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		11 interacting genes: ARHGDIA C15orf48 CHGB FAM107A FOXJ1 ILK MANF NISCH POT1 STAB1 TERF2IP	34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAFAZZIN TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1
Entrez ID		11344	1114
HPRD ID		08464	07512
Ensembl ID		ENSG00000247596	ENSG00000089199
Uniprot IDs		Q6IBS0	P05060
PDB IDs		2VAC 2W0I
Enriched GO Terms of Interacting Partners?
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