GABARAP and SEC62

Number of citations of the paper that reports this interaction (PubMedID 32620754)
5

Data Source:
BioGRID (unspecified method, x-ray crystallography)

		GABARAP	SEC62
Description		GABA type A receptor-associated protein	SEC62 homolog, preprotein translocation factor
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GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Lysosome Autophagosome Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Cytoplasmic Vesicle Cell Body Synapse Perinuclear Region Of Cytoplasm Sperm Midpiece	Endoplasmic Reticulum Rough Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	Signaling Receptor Activity
	Biological Process	Autophagosome Assembly Microtubule Cytoskeleton Organization Autophagy Of Mitochondrion Protein Targeting Cellular Response To Nitrogen Starvation Chemical Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Macroautophagy Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Rac Protein Signal Transduction Positive Regulation Of Protein K48-linked Ubiquitination	Cotranslational Protein Targeting To Membrane Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Posttranslational Protein Targeting To Membrane, Translocation
Pathways		Macroautophagy TBC/RABGAPs
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)	Cadmium levels ( 26025379)
Interacting Genes		61 interacting genes: AMBRA1 ANK2 ANK3 ATG101 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 ATXN3 BIRC6 CUL3 DMPK DVL2 FLCN GABRG1 GABRG2 GABRG3 GJA1 GPHN HDAC5 KBTBD7 KDR LMNB1 MAPK15 MEFV MIB1 MLH1 MPC1 MYBPC2 NBR1 NEDD4 NEK9 NSF OPTN PCM1 PGS1 PKP4 PRKCZ RB1CC1 SEC62 SNX18 SQSTM1 SRPK1 SRPK2 STK3 TAX1BP1 TBC1D25 TFRC TLE5 TP53INP1 TRIM21 TRIM32 TSR2 TTN TUBB3 ULK1 ULK2 VPS28	5 interacting genes: CIC GABARAP OGT SEC63 ZNF24
Entrez ID		11337	7095
HPRD ID		05496	03706
Ensembl ID		ENSG00000170296	ENSG00000008952
Uniprot IDs		O95166 Q6IAW1	D3DNQ1 Q99442
PDB IDs		1GNU 1KLV 1KM7 1KOT 3D32 3DOW 3WIM 4XC2 5DPS 6HB9 6HOG 6HOH 6HOJ 6HOK 6HYL 6HYM 6HYN 6HYO 7BRQ 7BRT 7BRU 7BV4	7BRT
Enriched GO Terms of Interacting Partners?
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