CHRM5 and STARD3NL

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		CHRM5	STARD3NL
Description		cholinergic receptor muscarinic 5	STARD3 N-terminal like
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse Postsynaptic Membrane	Lysosomal Membrane Endosome Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Organelle Membrane Contact Site Endoplasmic Reticulum-endosome Membrane Contact Site
	Molecular Function	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Serotonin Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity	Protein Binding Cholesterol Binding Protein Homodimerization Activity
	Biological Process	Gastric Acid Secretion G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Dopamine Transport Transmission Of Nerve Impulse Regulation Of Phosphatidylinositol Dephosphorylation G Protein-coupled Serotonin Receptor Signaling Pathway	Vesicle Tethering To Endoplasmic Reticulum
Pathways		Muscarinic acetylcholine receptors G alpha (q) signalling events	Pregnenolone biosynthesis
Drugs		Ziprasidone Amitriptyline Metixene Terfenadine Clozapine Doxylamine Trihexyphenidyl Loxapine Meperidine Imipramine Darifenacin Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine methylbromide Trimipramine Scopolamine Benzquinamide Propiomazine Brompheniramine Maprotiline Methantheline Tolterodine Promethazine Doxepin Desipramine Ketamine Quetiapine Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin ALKS 27 Fesoterodine Aclidinium Umeclidinium Dosulepin Etoperidone Homatropine Thonzylamine Revefenacin Propiverine Rociverine Aripiprazole lauroxil
Diseases
GWAS		Malaria ( 31844061)	Bone mineral density (spine) ( 19801982) Fractures ( 30158200 30598549) Frontotemporal dementia with GRN mutation ( 29724592) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 31453325 30598549 28869591) Heel bone mineral density variance ( 31453325) Height ( 20881960 25282103 25429064 31562340) Lumbar spine bone mineral density ( 22504420) Lumbar spine bone mineral density (integral) ( 27476799) Mosquito bite size ( 28199695) Rosacea symptom severity ( 29771307) Treatment response for severe sepsis ( 22310353)
Interacting Genes		32 interacting genes: ASPH ASTN2 ATP2A2 ATP9A CBFB CD82 EPB41L1 EPC1 ERCC1 GJB6 GOLGA8A GPRASP1 HLA-F MAP3K1 MSMO1 MYH7 NLE1 NPAS3 PRSS16 REEP5 RGS7 RTN1 SCAND2P SLC2A6 SLC5A6 SLC6A8 SMAD6 SNCA SPNS1 STARD3NL TMEM161A USP33	3 interacting genes: CHRM5 ELK1 HCST
Entrez ID		1133	83930
HPRD ID		00331	18117
Ensembl ID		ENSG00000184984	ENSG00000010270
Uniprot IDs		A0A024R9I2 P08912 Q8IVW0	A0A024RA89 O95772
PDB IDs		6OL9
Enriched GO Terms of Interacting Partners?
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