CHRM3 and GNAS

  • Number of citations of the paper that reports this interaction (PubMedID 28298427)
  • 23
  • Data Source:
  • BioGRID (two hybrid)

CHRM3

GNAS

Description cholinergic receptor muscarinic 3 GNAS complex locus
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic obstructive pulmonary disease ( 30804561)
  • Colorectal cancer ( 29228715)
  • Depression in smokers ( 30219690)
  • Electroencephalogram traits ( 25387704)
  • Feeling worry ( 29500382)
  • FEV1 ( 30804560)
  • Generalized epilepsy ( 22949513)
  • Gut microbiota beta diversity (weighted UniFrac distance) ( 33208821)
  • Hallucinations in long-term cannabis use ( 31740666)
  • Hypertension ( 17554300)
  • Interleukin-6 (red blood cell fatty acid level interaction) ( 28820441)
  • Lung function (FEV1/FVC) ( 28166213 30804560)
  • Peak expiratory flow ( 30804560)
  • Platelet count ( 21507922)
  • Post bronchodilator FEV1 ( 26634245)
  • Reflection (response to stress) ( 30886212)
  • Sulfasalazine-induced agranulocytosis ( 28762467)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes 26 interacting genes: ARF1 ARF6 BSG CALM3 CCDC184 CD2BP2 COMMD7 CSNK1A1 GNAQ GNAS GPRASP1 GRK6 GZMB JAKMIP1 MAGED2 PDGFRB POM121C PPP1R9B RAB5IF RGS7 SEPTIN3 SET SGSM3 TAP1 TPM3 YIPF3 42 interacting genes: ADCY2 ADCY5 ADCY6 ADORA1 ADRB2 ADRB3 AVPR2 AXIN1 CALM1 CAV3 CHEK2 CHRM3 CRHR1 CYSLTR2 DRD5 EGFR FZD7 GCGR GLP1R GNB1 GNGT1 HTR6 LHB LHCGR MSANTD3 MTNR1B NUCB1 NUCB2 OPTN PANX1 PTGDR PTGIR PTGIS RGS2 RIC8A RIC8B RXFP3 SNX13 TBXA2R TSHR TTC1 VIPR1
Entrez ID 1131 2778
HPRD ID 00329 00761
Ensembl ID ENSG00000133019 ENSG00000087460
Uniprot IDs A0A024R3W1 P20309 A0A0S2Z3H8 A0A0S2Z3S5 A0A590UJF0 B0AZR9 O95467 P63092 P84996 Q14455 Q5FWY2 Q5JWD1 Q5JWF2
PDB IDs 2CSA 5G53 5UZ7 5VAI 6AU6 6B3J 6E3Y 6E67 6EG8 6GDG 6LI3 6LMK 6LPB 6M1H 6M1I 6NI3 6NIY 6ORV 6P9X 6P9Y 6PB0 6PB1 6UUN 6UUS 6UVA 6VCB 6VN7 6WHC 6WI9 6WPW 6WZG 6X18 6X19 6X1A 6XOX 7BW0 7BZ2 7C2E 7CFM 7CFN 7CKW 7CKX 7CKY 7CKZ 7CRH 7CZ5 7D3S 7D7M 7DHI 7DHR 7JV5 7JVP 7LCI
Enriched GO Terms of Interacting Partners?
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