RASSF1 and TUBG1

Number of citations of the paper that reports this interaction (PubMedID 14603253)
61

Data Source:
HPRD (in vitro, in vivo)

		RASSF1	TUBG1
Description		Ras association domain family member 1	tubulin gamma 1
Image
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Microtubule Cytoskeleton	Pericentriolar Material Condensed Nuclear Chromosome Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Centriole Spindle Polar Microtubule Cytosol Microtubule Cytoplasmic Microtubule Cell Leading Edge Ciliary Basal Body Apical Part Of Cell Recycling Endosome Non-motile Cilium Mitotic Spindle Microtubule
	Molecular Function	Protein Binding Zinc Ion Binding	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Identical Protein Binding
	Biological Process	Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Cell Cycle Regulation Of Microtubule Cytoskeleton Organization	Mitotic Sister Chromatid Segregation Meiotic Spindle Organization Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Mitotic Spindle Organization Cytoplasmic Microtubule Organization
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs			Vinblastine
Diseases
GWAS		Basophil percentage of white cells ( 32888494) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 30285260) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Interacting Genes		73 interacting genes: AKT1 ARAF ATM ATP2B4 ATR ATRX AURKA AURKB BANF1 BRAF C7orf25 C8orf33 CCND2 CCNE1 CDC20 CDK4 CDK6 CDKN2A CDKN2B CLNK CNKSR1 DAXX DDB1 E4F1 EPHA2 ERBB2 EXOSC8 FGFR4 FZR1 GLIS2 GRM1 HRAS IGFBP5 KAT2A KCNE3 KDELR2 KDM1A LARS2 LATS2 MAP1B MAP1S MAP2K3 MAP2K6 MAPK8 MDM2 MET MOAP1 MST1 MYC NF2 NUDT10 PFDN5 PRKDC RAF1 RASSF5 RELA RHOA RHOU SMARCA4 STK11 STK4 SUV39H1 SUV39H2 TEAD2 TERT TMEM115 TMEM158 TNFRSF10A TNFRSF1A TSC1 TUBB TUBG1 XPA	35 interacting genes: APP BRCA1 CENPJ CNTN2 CTRL CUL4A DDX41 IKBKG KIF14 KRT18 KRT19 MARK4 NAPG NDE1 OGT PCNT PHB PIK3R1 PLK1 PXN RACGAP1 RACK1 RARA RASSF1 RND2 RNF19A RPGR SGCA SPATC1 TUBA1B TUBA3C TUBB4B TUBGCP3 TUBGCP4 WNT3
Entrez ID		11186	7283
HPRD ID		05470	01853
Ensembl ID		ENSG00000068028	ENSG00000131462
Uniprot IDs		Q9NS23	P23258
PDB IDs		2KZU	1Z5V 1Z5W 3CB2 6V5V 6V6S 7AS4
Enriched GO Terms of Interacting Partners?
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