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CORO1A and THBS1
Number of citations of the paper that reports this interaction (PubMedID
10749676
)
3
Data Source:
HPRD
(in vitro)
CORO1A
THBS1
Description
coronin 1A
thrombospondin 1
Image
No pdb structure
GO Annotations
Cellular Component
Immunological Synapse
Phagocytic Cup
Nucleus
Cytoplasm
Early Endosome
Cytosol
Actin Filament
Plasma Membrane
Cell-cell Junction
Membrane
Lamellipodium
Axon
Phagocytic Vesicle Membrane
Cortical Actin Cytoskeleton
Protein-containing Complex
Phagocytic Vesicle
Extracellular Exosome
Glutamatergic Synapse
Extracellular Region
Fibrinogen Complex
Extracellular Space
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
External Side Of Plasma Membrane
Cell Surface
Sarcoplasmic Reticulum
Secretory Granule
Extracellular Matrix
Platelet Alpha Granule
Platelet Alpha Granule Lumen
Collagen-containing Extracellular Matrix
Extracellular Exosome
Molecular Function
RNA Binding
Actin Binding
Actin Monomer Binding
Protein Binding
Protein C-terminus Binding
Cytoskeletal Protein Binding
Myosin Heavy Chain Binding
Protein Homodimerization Activity
Phosphatidylinositol 3-kinase Binding
Actin Filament Binding
Phosphatidylserine Binding
Fibronectin Binding
Integrin Binding
Extracellular Matrix Structural Constituent
Calcium Ion Binding
Protein Binding
Heparin Binding
Fibroblast Growth Factor Binding
Low-density Lipoprotein Particle Binding
Identical Protein Binding
Laminin Binding
Proteoglycan Binding
Transforming Growth Factor Beta Binding
Fibrinogen Binding
Collagen V Binding
Biological Process
Immunological Synapse Formation
Phagolysosome Assembly
Calcium Ion Transport
Phagocytosis
Actin Filament Organization
Regulation Of Cell Shape
Cell Migration
Actin Cytoskeleton Organization
Positive Regulation Of Cell Migration
Leukocyte Chemotaxis
Negative Regulation Of Vesicle Fusion
Cell-substrate Adhesion
Uropod Organization
Regulation Of Actin Cytoskeleton Organization
Nerve Growth Factor Signaling Pathway
Positive Regulation Of T Cell Proliferation
T Cell Homeostasis
Natural Killer Cell Degranulation
Negative Regulation Of Neuron Apoptotic Process
Innate Immune Response
Homeostasis Of Number Of Cells Within A Tissue
Positive Chemotaxis
Negative Regulation Of Actin Nucleation
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Early Endosome To Recycling Endosome Transport
Cellular Response To Interleukin-4
Response To Hypoxia
Negative Regulation Of Endothelial Cell Proliferation
Negative Regulation Of Cell-matrix Adhesion
Sprouting Angiogenesis
Chronic Inflammatory Response
Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Negative Regulation Of Dendritic Cell Antigen Processing And Presentation
Inflammatory Response
Immune Response
Response To Unfolded Protein
Cell Adhesion
Positive Regulation Of Cell Population Proliferation
Response To Mechanical Stimulus
Response To Glucose
Positive Regulation Of Endothelial Cell Migration
Negative Regulation Of Endothelial Cell Migration
Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane
Negative Regulation Of Nitric Oxide Mediated Signal Transduction
Negative Regulation Of CGMP-mediated Signaling
Negative Regulation Of Plasminogen Activation
Positive Regulation Of Macrophage Chemotaxis
Positive Regulation Of Fibroblast Migration
Cell Migration
Negative Regulation Of Angiogenesis
Peptide Cross-linking
Positive Regulation Of Blood Coagulation
Positive Regulation Of Cell Migration
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Response To Magnesium Ion
Response To Progesterone
Negative Regulation Of Interleukin-12 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Transforming Growth Factor Beta1 Production
Response To Testosterone
Cellular Response To Heat
Response To Endoplasmic Reticulum Stress
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Phosphorylation
Positive Regulation Of Macrophage Activation
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of MAP Kinase Activity
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Engulfment Of Apoptotic Cell
Positive Regulation Of Translation
Positive Regulation Of Angiogenesis
Behavioral Response To Pain
Positive Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Chemotaxis
Response To Calcium Ion
Regulation Of Cell Cycle
Negative Regulation Of Focal Adhesion Assembly
Positive Regulation Of Protein Kinase B Signaling
Negative Regulation Of Fibrinolysis
Cellular Response To Tumor Necrosis Factor
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Sprouting Angiogenesis
Positive Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Negative Regulation Of Endothelial Cell Chemotaxis
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Prevention of phagosomal-lysosomal fusion
Platelet degranulation
Signaling by PDGF
Integrin cell surface interactions
Syndecan interactions
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Hodgkin's lymphoma (
30194254
)
Tonsillectomy (
27182965
28928442
)
Cortical volume (
32963231
)
Liver enzyme levels (alanine transaminase) (
33972514
)
Logical memory (immediate recall) in normal cognition (
29274321
)
Urate levels (
31578528
)
Interacting Genes
20 interacting genes:
ACTB
FHL3
FSD2
FXR1
GIT2
GOLGA2
IFT20
LMO2
MAGEA11
MAGOH
NCF4
POLR1C
POT1
SMAD3
SMARCD1
SPATA20
STAT3
TAB1
THBS1
YTHDC1
43 interacting genes:
CALCR
CALR
CD36
CD47
CFH
COL1A1
COL2A1
COL3A1
COL4A1
COL5A1
COL7A1
CORO1A
CTSG
DCN
DHFR
ELANE
F2
FGA
FGF2
FN1
HRG
HSP90AA1
IGFBP5
ITGB3
JAG1
KCNQ3
KNG1
LAMB3
LRP1
LRP2
LRP5
MMP2
MMP9
MTDH
PDGFB
PLCB2
PLG
SCARB2
SPARC
TFPI
TGFB1
TNFAIP6
TNFRSF11B
Entrez ID
11151
7057
HPRD ID
05414
01765
Ensembl ID
ENSG00000102879
ENSG00000137801
Uniprot IDs
A0A024R611
P31146
P07996
PDB IDs
1LSL
1UX6
1Z78
1ZA4
2ERF
2ES3
2OUH
2OUJ
3R6B
5FOE
Enriched GO Terms of Interacting Partners
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